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The Journal of Ultrasound in Medicine recently published an article titled "Two-Dimensional Shear Wave Elastography: Utility in Differentiating Gallbladder Cancer From Chronic Cholecystitis" by Soundararajan et al. The authors conducted a prospective study comparing shear wave (SW) values between gallbladder cancer and chronic cholecystitis as a screening tool for patients with gallbladder wall thickening. They found that the mean SW value was significantly higher in gallbladder cancer patients compared to chronic cholecystitis patients. However, the study has some limitations, including the lack of data on intra- and interobserver variability and the absence of surgically resected gallbladder cancer cases. The authors' suggestions provide valuable insights for performing two-dimensional shear wave elastography for patients with gallbladder disease. [Extracted from the article]

The Journal of Ultrasound in Medicine recently published an article on the strategy for accurate diagnosis of focal liver lesions using contrast-enhanced ultrasound. While the authors' suggestions are generally agreeable, there are some questions and thoughts regarding their description. The authors divided patients into intermediate and low-risk groups based on certain factors, but it is unclear why they did not consider type 2 diabetes mellitus or other metabolic diseases, which have been independently associated with hepatocellular carcinoma (HCC) development. The study also did not provide separate results for different benign pathologies, making it difficult to fully understand the findings. Additionally, the authors should clarify if HCC cases in the low-risk group exhibit arterial hyperenhancement with washout, as seen in other HCCs. The definition of washout used in the study is also imprecise. Overall, the article provides valuable insights for performing contrast-enhanced ultrasound in patients with intermediate and low-risk groups. [Extracted from the article]

Generally speaking, surgical tumor resection is performed by determining the resection margin 4-10 mm outwards based on visual observation boundaries (VOB), because it is extremely challenging to determine accurately the tumor extent before histological examination. Keywords: basal cell carcinoma; diagnostic problem; shear wave ultrasound; skin; ultrasound EN basal cell carcinoma diagnostic problem shear wave ultrasound skin ultrasound 2685 2686 2 10/18/23 20231101 NES 231101 Basal cell carcinoma (BCC) is the most common cutaneous tumor, mostly involving the head and neck.[1] It is absolutely necessary to preserve as much surrounding normal skin as possible as well as remove the tumor without leaving tumor tissue. [Extracted from the article]