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We sought to understand the impact of sparing extracellular matrix at the site of irreversible electroporation (IRE) on ablation zone involution in patients treated for liver tumors, in comparison to microwave ablation (MWA), while determining the influence of functional liver status on these outcomes The difference between ablation modalities on ablation zone involution and laboratory values were evaluated using generalized estimating equations to account for the correlation due to longitudinal measurements on the same patient. [Extracted from the article]

Abstract No. 381 Cone Beam computed tomography-based virtual injection software could help catheter positioning for selective treatment delivery in liver-directed therapy To evaluate accuracy of a cone-beam CT-based virtual injection algorithm designed to determine optimal catheter position for treatment delivery during liver-directed therapy Virtual injection algorithm is accurate and reliable in identification of tumor-supplying vessel and can help determine catheter selective position during cone-beam CT-guided liver-directed therapies. [Extracted from the article]

To determine the relationship of radiation dose to imaging response, survival, and toxicity after radioembolization (RE) of liver metastasis from breast cancer. Patients with grade 3 hepatotoxicity received significantly greater dose to normal liver (97 ± 81 Gy) compared with those without hepatoxicity (62 ± 47 Gy) (P = 0.038). In planning RE for these patients, assessment of predicted dose to tumor and normal liver can help in prognostication and patient selection. [Extracted from the article]

To determine the relationship of ablation margin with overall survival (OS), time to progression (TTP) and local recurrence after percutaneous thermal ablation of liver, lung and bone/soft tissue metastases from oligometastatic breast cancer (BC). Overall, 85% of patients had no local tumor progression; no local progression occurred with ablation margins >=5 mm. [Extracted from the article]