1. Seeding of arteriovenous prostheses with homologous endothelium
- Author
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Zhi R. Gao, George P. Noon, Christopher L. Ives, L. T. Navarro, Donald G. Weilbaecher, and Jose L. Zamora
- Subjects
Pathology ,medicine.medical_specialty ,Endothelium ,business.industry ,medicine.medical_treatment ,food and beverages ,Expanded polytetrafluoroethylene ,Prosthesis ,Surgery ,Endothelial stem cell ,medicine.anatomical_structure ,Preliminary report ,Homologous chromosome ,medicine ,Seeding ,Cardiology and Cardiovascular Medicine ,business ,Artery - Abstract
Endothelial cell seeding of expanded polytetrafluoroethylene (e-PTFE) arteriovenous prostheses was performed to compare seeding with homologous vs. autologous cells and to study the effect of homologous seeding with a larger vs. a smaller number of cells. Sixteen dogs were randomly assigned to four equal groups: I, control; II, light homologous seeded; III, heavy homologous seeded; and IV, autologous seeded. Bilateral femoral arteriovenous loop grafts were inserted in all. Efficiency of seeding was assessed by cell counts of instilled vs. retained cells. All grafts remained patent and were harvested approximately 8 weeks after implantation. Samples were evaluated grossly by scanning electron microscopy and light microscopy. There was a direct correlation between number of cells instilled and number retained for each graft; group III received and retained the largest number (p
- Published
- 1986
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