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Your search keyword '"Carrillo, Elena"' showing total 1 results
Start Over Author "Carrillo, Elena" Topic rna interference Journal journal of virological methods
1 results on '"Carrillo, Elena"'

1. The search for a T cell line for testing novel antiviral strategies against HIV-1 isolates of diverse receptor tropism and subtype origin.

Author

Herrera-Carrillo, Elena, Paxton, William A., and Berkhout, Ben

Subjects
*T cells, *ANTIVIRAL agents, *VIRAL tropism, *HIV, *CELL lines, *RNA interference, *VIRAL replication
Abstract

Highlights: [•] The use of T cell lines to replace PBMCS for HIV-1 studies has been studied. [•] The PM1 T cell line supports the replication of all HIV-1 subtypes. [•] The PM1 T cell line supports CCR5- and CXCR4-using HIV-1 variants. [•] The safety and efficacy of an RNAi-based anti-HIV gene therapy were evaluated. [•] The PM1 cells provide a valuable tool for basic and applied HIV-1 studies. [ABSTRACT FROM AUTHOR]

Published
2014
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