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Your search keyword '"Piccirilli, Giulia"' showing total 2 results
Start Over Author "Piccirilli, Giulia" Journal journal of virological methods
2 results on '"Piccirilli, Giulia"'

2. Clinical evaluation of the new Roche platform of serological and molecular cytomegalovirus-specific assays in the diagnosis and prognosis of congenital cytomegalovirus infection

Author

Claudia Pavia, Marcello Lanari, Giuliana Simonazzi, Maria Grazia Capretti, Giulia Piccirilli, Angela Chiereghin, Liliana Gabrielli, Gabriele Turello, Dino Gibertoni, Tiziana Lazzarotto, Diego Squarzoni, Chiereghin, Angela, Pavia, Claudia, Gabrielli, Liliana, Piccirilli, Giulia, Squarzoni, Diego, Turello, Gabriele, Gibertoni, Dino, Simonazzi, Giuliana, Capretti, MARIA GRAZIA, Lanari, Marcello, and Lazzarotto, Tiziana

Subjects
0301 basic medicine, Amniotic fluid, Prognosi, 030106 microbiology, Congenital cytomegalovirus infection, Antibody Affinity, Cytomegalovirus, Urine, Biology, Roche Diagnostics, Antibodies, Viral, Sensitivity and Specificity, Immunoglobulin G, Serology, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Virology, medicine, Humans, Avidity, Serologic Tests, 030212 general & internal medicine, Retrospective Studies, Clinical Laboratory Techniques, Infant, Newborn, virus diseases, Cytomegaloviru, medicine.disease, Prognosis, Immunoglobulin M, Molecular Diagnostic Techniques, Immunology, Cytomegalovirus Infections, DNA, Viral, biology.protein, Female, Reagent Kits, Diagnostic, Diagnosi
Abstract

Clinical evaluation of the Elecsys(®) CMV IgM, IgG, IgG Avidity and COBAS AmpliPrep/COBAS TaqMan CMV (COBAS CMV) assays (Roche Diagnostics AG) in the diagnosis and prognosis of congenital CMV infection was performed. In this study, 150 preselected clinical samples (50 primary infection sera, 50 amniotic fluid [AF] and 50 newborn urine) were processed using Roche serological/molecular CMV-specific tests. Results were compared with those obtained by routine assays (comparator assays). The Elecsys(®) CMV IgM and IgG assays showed a perfect agreement (100%) with the comparator assays. Using the combination of the Elecsys(®) CMV IgM and IgG Avidity assays results, a primary infection was identified in 100% of cases. Inappropriate avidity CMV IgG values in two samples with very low IgG values (

Published
2017

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