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Your search keyword '"Kegong Tian"' showing total 4 results
Start Over Author "Kegong Tian" Journal journal of virology
4 results on '"Kegong Tian"'

1. Complete Genome Sequence of an Overattenuated Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

Author

Jiajun Wu, Lilin Wang, Xiuling Yu, Zhi Zhou, Jishu Shi, Wei Han, Xiangdong Li, Kegong Tian, Xiaoyu Deng, Nanhua Chen, and Zhen Cao

Subjects
Swine, viruses, Molecular Sequence Data, Immunology, Mutation, Missense, Virulence, Genome, Viral, Biology, Microbiology, Virus, Serial passage, Virology, Animals, Point Mutation, Porcine respiratory and reproductive syndrome virus, Serial Passage, Sequence Deletion, chemistry.chemical_classification, Whole genome sequencing, Genetics, Point mutation, Sequence Analysis, DNA, Porcine reproductive and respiratory syndrome virus, biology.organism_classification, Genome Announcements, Amino acid, Vaccination, chemistry, Insect Science, RNA, Viral
Abstract

JXA1-P170 is an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) that has been passaged in vitro 170 times. Vaccination with JXA1-P170 cannot protect pigs against JXA1 challenge. Compared with the parental virus JXA1, JXA1-P170 contains 1 nucleotide (nt) deletion and 113 nt mutations leading to 59 amino acid substitutions. Here we announce the first complete genome sequence of the overattenuated HP-PRRSV.

Published
2012

2. A Novel Porcine Circovirus Type 2a Strain, 10JS-2, with Eleven-Nucleotide Insertions in the Origin of Genome Replication

Author

Jianqiang Ni, Dongmei Hu, Xinyan Zhai, Li Xiaoxia, Zhi Zhou, Xue Han, Kegong Tian, Lin Cai, Xiuling Yu, and Wang Baoyue

Subjects
Circovirus, DNA Replication, Swine, animal diseases, viruses, Molecular Sequence Data, Immunology, Genome, Viral, Microbiology, Genome, Phylogenetics, Virology, Replication (statistics), Animals, Nucleotide, Circoviridae Infections, Phylogeny, Swine Diseases, chemistry.chemical_classification, Genetics, Base Sequence, biology, Strain (biology), DNA replication, virus diseases, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Genome Announcements, Mutagenesis, Insertional, Porcine circovirus, chemistry, Insect Science
Abstract

Here, we report a novel porcine circovirus type 2a (PCV2a) strain with 11 nucleotides (nt) inserted in the origin of genome replication (Ori). This is the first report of a PCV2a strain with nucleotide insertion in Ori. Our study will help further epidemiological studies and extend our knowledge of evolutionary characteristics of PCV2.

Published
2012

3. A Novel Porcine Circovirus Type 2a Strain, 10JS-2, with Eleven-Nucleotide Insertions in the Origin of Genome Replication.

Author

Lin Cai, Xue Han, Dongmei Hu, Xiaoxia Li, Baoyue Wang, Jianqiang Ni, Zhi Zhou, Xiuling Yu, Xinyan Zhai, and Kegong Tian

Subjects
*CIRCOVIRUSES, *LABORATORY swine, *NUCLEOTIDES, *DNA insertion elements, *VIRAL replication, *VIRAL genomes, *EPIDEMIOLOGY, *VIRUS phylogeny
Abstract

Here, we report a novel porcine circovirus type 2a (PCV2a) strain with 11 nucleotides (nt) inserted in the origin of genome replication (Ori). This is the first report of a PCV2a strain with nucleotide insertion in Ori. Our study will help further epidemiological studies and extend our knowledge of evolutionary characteristics of PCV2. [ABSTRACT FROM AUTHOR]

Published
2012
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4. Complete Genome Sequence of Two Novel Chinese Virulent Porcine Reproductive and Respiratory Syndrome Virus Variants.

Author

Zhi Zhou, Xiangdong Li, Qi Liu, Dongmei Hu, Xiaojuan Yue, Jianqiang Ni, Xiuling Yu, Xinyan Zhai, Galliher-Beckley, Amy, Chen, Nanhua, Shi, Jishu, and Kegong Tian

Subjects
*VIRAL genomes, *NUCLEOTIDE sequence, *PORCINE reproductive & respiratory syndrome, *VIRAL variation, *VIRUS virulence, *DELETION mutation, *VIRAL proteins
Abstract

A highly pathogenic strain of porcine reproductive and respiratory syndrome virus (PRRSV), characterized by a discontinuous 30-amino-acid deletion in its Nsp2-coding region, has been emerging in China since 2006. Here, we report the complete genomic sequence of two novel Chinese virulent PRRSV variants with additional NSP2-gene deletions, which will help us understand the molecular and evolutionary characteristics of PRRSV in Asia [ABSTRACT FROM AUTHOR]

Published
2012
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