1. [The comparative analysis of the surgical treatment of the familial adenomatosis of the colon with the use of cell transplantation].
- Author
-
Shelygin IuA, Kuz'minov AM, Vyshegorodtsev DV, Kapuller LL, Chubarov IuIu, Vlasov SB, and Sukhikh GT
- Subjects
- Adenomatous Polyposis Coli pathology, Adult, Colon pathology, Colonic Pouches, Comparative Effectiveness Research, Disease-Free Survival, Female, Humans, Ileum surgery, Male, Secondary Prevention, Treatment Outcome, Adenomatous Polyposis Coli surgery, Cell Transplantation methods, Colectomy adverse effects, Colectomy methods, Colon surgery, Fetus cytology, Intestinal Mucosa pathology, Intestinal Mucosa surgery, Rectum pathology, Rectum surgery
- Abstract
Authors represent the surgical technique of colectomy with preserving the natural intestinal passage in the treatment of the familial colic adenomatosis. The technique is based on the preserving the distal part of the rectum with its demucosation and connecting with the ileal conduit. The rectal mucosa reconstruction is performed with the use of allogenic transplantation of fetal intestinal cells. 27 patients were operated on. The rectal mucosa reconstruction was registered in all cases range 4-12 weeks postoperatively. The long-term follow-up showed no disease recurrence within 5 years. The method demonstrated better intermediate and long-term functional results.
- Published
- 2012