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On the basis of 1800 examinations of tumor cells the authors show possibility for accumulation of luminescent dye uranine by malignant cells. The conception of the mechanism of its accumulation, confirmed by the studies of reinoculated tumors of rats (60 examinations) is presented. Of 821 patients with ulcers of the stomach 641 had no luminescence; at repeated examination cancer and ulcer were revealed in 7 of them. Malignant transformation was verified by histologic method in 102 of 180 patients with luminescent ulcers. In 22 patients intestinal metaplasia was detected in the luminescence areas and in 40--there was a rough epitnelial dysplasia. At the examination of these patients two years later, cancer of the stomach at the sites of previously revealed luminescence was detected in 15 patients (26.3%).

The study was conducted in 90 children aged from 5 months to 14 years during radiologically-guided endovascular (RIV) interventions with bolus injection of radiocontrast agents (RCA) in a dose of 2-3 ml/kg for 2-3 sec. High-osmolality RCA were used in 80 children, an nonionic low-osmolality RCA omnipaque-300 in 10 children. Injection of RCA bolus was attended by marked acute disorders of blood colloidoosmotic equilibrium (COE) which depended on the initial status of the latter and were greater when high osmolality RCA were used. On the basis of the study results, the authors developed and tested a method of modulator infusion therapy with consideration for the initial blood COE (hyper-, normo-, hypoosmolality). The suggested therapy makes it possible to reduce the degree of blood COE disorders considerably and prevent the development of complications associated with disturbed osmoregulation.