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Your search keyword '"Makino, Hirofumi"' showing total 25 results
Start Over Author "Makino, Hirofumi" Journal kidney international
25 results on '"Makino, Hirofumi"'

4. The classification of glomerulonephritis in systemic lupus erythematosus revisited

Author

WEENING, JAN J., DʼAGATI, VIVETTE D., SCHWARTZ, MELVIN M., SESHAN, SURYA V., ALPERS, CHARLES E., APPEL, GERALD B., BALOW, JAMES E., BRUIJN, JAN A., COOK, TERENCE, FERRARIO, FRANCO, FOGO, AGNES B., GINZLER, ELLEN M., HEBERT, LEE, HILL, GARY, HILL, PRUE, JENNETTE, J. CHARLES, KONG, NORELLA C., LESAVRE, PHILIPPE, LOCKSHIN, MICHAEL, LOOI, LAI-MENG, MAKINO, HIROFUMI, MOURA, LUIZ A., and NAGATA, MICHIO

Published
2004

15. Management of patients with diabetes and CKD: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

Author

Perkovic, Vlado, primary, Agarwal, Rajiv, additional, Fioretto, Paola, additional, Hemmelgarn, Brenda R., additional, Levin, Adeera, additional, Thomas, Merlin C., additional, Wanner, Christoph, additional, Kasiske, Bertram L., additional, Wheeler, David C., additional, Groop, Per-Henrik, additional, Bakris, George L., additional, Cooper, Mark E., additional, Chae, Dong-Wan, additional, Davidson, Michael H., additional, de Boer, Ian H., additional, de Zeeuw, Dick, additional, Fornoni, Alessia, additional, Gnudi, Luigi, additional, Herzog, Charles A., additional, Hung, Adriana M., additional, Jafar, Tazeen Hasan, additional, Jardine, Meg, additional, Jha, Vivekanand, additional, Ji, Linong, additional, Kahn, Steven E., additional, Langham, Robyn G., additional, Lerma, Edgar V., additional, Ma, Ronald C.W., additional, Makino, Hirofumi, additional, Marre, Michel, additional, Mauer, Michael, additional, Metsärinne, Kaj, additional, Nelson, Robert G., additional, Pecoits-Filho, Roberto, additional, Pollock, Carol A., additional, Rajapurkar, Mohan, additional, Rossing, Peter, additional, Rychlík, Ivan, additional, Sharma, Kumar, additional, Stanton, Robert C., additional, Tesař, Vladimír, additional, Tikkanen, Ilkka, additional, Tomson, Charlie R.V., additional, Toto, Robert D., additional, Tsukamoto, Yusuke, additional, Tuttle, Katherine R., additional, Wada, Takashi, additional, Williams, Winfred W., additional, Zhang, Hong, additional, and Zoungas, Sophia, additional

Published
2016
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16. Right hypoplastic kidney

Author

Ogawa, Ayu, primary, Kitamura, Shinji, additional, Nakayama, Kazunori, additional, Sugiyama, Hitoshi, additional, Morisada, Naoya, additional, Iijima, Kazumoto, additional, and Makino, Hirofumi, additional

Published
2012
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25. VASCULAR BIOLOGY - HEMODYNAMICS - HYPERTENSION The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats.

Author

Hiragushi, Keita, Wada, Jun, Eguchi, Jun, Matsuoka, Takashi, Yasuhara, Akihiro, Hashimoto, Izumi, Yamashita, Tetsuji, Hida, Kazuyuki, Nakamura, Yoshio, Shikata, Kenichi, Minamino, Naoto, Kangawa, Kenji, and Makino, Hirofumi

Subjects
*HEMODYNAMICS, *ADRENOMEDULLIN, *VASODILATION, *HORMONE receptors, *STREPTOZOTOCIN, *LABORATORY rats
Abstract

The role of adrenomedullin and receptors in glomerular hyperfiltration in streptozotocin-induced diabetic rats. Background. Since adrenomedullin (AM) elicits vasodilatation by binding to specific AM receptors consisted of calcitonin-receptor-like receptor (CRLR)/receptor-activity-modifying protein 2 (RAMP2) or CRLR/receptor-activity-modifying protein 3 (RAMP3) on endothelial cells and stimulating nitric oxide production, AM possibly involves in glomerular capillary dilatation in early phase of diabetic nephropathy. Methods. Streptozotocin (STZ)-induced diabetic Sprague-Dawley rats at 4 weeks after the injection were employed for expression studies of AM, RAPM2, and RAMP3. The measurement of AM peptide levels in kidney tissue, plasma, and urine was performed. Human aortic endothelial cells (HAEC) were used to investigate functional link between glucose-induced AM production and nitric oxide release. Results. STZ rats showed glomerular hypertrophy and increased urinary NO2− and NO3− excretion. By Northern blot analyses, AM and RAPM2 mRNAs significantly increased in the kidneys of STZ rats, while RAMP3 mRNA was not altered. In STZ rats, AM peptide was actively secreted into urine (1280 ± 360 fmol/day vs. control 110 ± 36 fmol/day). AM peptide was mainly detected on cortical and medullary collecting duct cells in control rat kidneys and AM peptide and mRNA were up-regulated on afferent arterioles and glomeruli of STZ rats. RAMP2 expression was detected on afferent arterioles and not in glomeruli in control rats and it was up-regulated on glomerular endothelial cells in STZ rats. In HAEC culture, d-glucose stimulated AM and nitric oxide production and they were suppressed by addition of AM antisense oligodeoxynucleotides. Conclusion. Up-regulated expression of AM and RAMP2 in afferent arterioles and glomeruli may be related to selective dilatation of glomerular capillary in acute phase of type 1 diabetes. [ABSTRACT FROM AUTHOR]

Published
2004
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