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Your search keyword '"Fernández-Fernández, Beatriz"' showing total 3 results
Start Over Author "Fernández-Fernández, Beatriz" Journal kidney international reports
3 results on '"Fernández-Fernández, Beatriz"'

1. Renal Disease in Metabolic Syndrome: the Hidden Role of Intrarenal Ischemia

Author

Hojs, Radovan, Bevc, Sebastjan, Fernández, Gema, Cases Corona, Clara María, Quero, María, Pujol, Laia, Montserrat Gomà, Sergi Beato, Cruzado, Josep, Ibernon, Meritxell, Moreso, Francisco, López-Martínez; Mads Hornum, Marina, Feldt-Rasmussen; Alberto Ortíz, Bo, Fernández-Fernandez, Beatriz, Gomá-Garces, Elena, Stock da Cunha, Teresa, Sanz, Ana B., Garranzo, María, Gonzalez-Enguita, Carmen, Autrán-Gómez; Pablo Cannata, Ana María, Khazim, Khalid, Ghanem, Fedaa, Porrini, Esteban, Rodríguez-Rodríguez, Rosa, Mena, Natalia Negrín, Ivo Laranjinhia, Tomás Concepción, Miguel Bigotte Vieira, Luís Mendonça, Francesco, Trevisani, Bettiga, Arianna, Di Marco, Federico, Salonia, Andrea, Montorsi, Francesco, Giacomo, Dell'Antonia, Morales, Enrique, Praga, Manuel, Hornum, Mads, Rodríguez Rodríguez, Ana Elena, Trevisani, Francesco, Fernández-Fernández, Beatriz, Cruzado, Josep María, Díaz, Maruja Navarro, Carro, Clara García, Khazim, Khaled, Ibernón, Meritxell, Laranjinhia, Ivo, Mendonça, Luís, Vieira, Miguel Bigotte, Feldt-Rasmussen, Bo, Ortiz, Alberto, Bagi, Per, and Sorensen, Cristian Acosta

Published
2024
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2. The Role of Vascular Lesions in Diabetes Across a Spectrum of Clinical Kidney Disease

Author

Rodríguez-Rodríguez, Rosa, Hojs, Radovan, Trevisani, Francesco, Morales, Enrique, Fernández, Gema, Bevc, Sebastjan, Cases Corona, Clara María, Cruzado, Josep María, Quero, María, Navarro Díaz, Maruja, Bettiga, Arianna, Di Marco, Federico, López Martínez, Marina, Moreso, Francisco, García Garro, Clara, Khazim, Khaled, Ghanem, Fedaa, Praga, Manuel, Ibernón, Meritxell, Laranjinha, Ivo, Mendonça, Luís, Bigotte Vieira, Miguel, Hornum, Mads, Feldt-Rasmussen, Bo, Fernández-Fernández, Beatriz, Concepción, Patricia Fox, Negrín Mena, Natalia, Ortiz, Alberto, and Porrini, Esteban

Published
2021
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3. Renal Disease in Metabolic Syndrome: the Hidden Role of Intrarenal Ischemia.

Author

Rodríguez-Rodríguez R, Hornum M, Rodríguez Rodríguez AE, Bevc S, Trevisani F, Fernández G, Hojs R, Fernández-Fernández B, Cases Corona CM, Cruzado JM, Quero M, Díaz MN, Bettiga A, Moreso F, Carro CG, Khazim K, Ghanem F, Ibernón M, Laranjinhia I, Mendonça L, Vieira MB, Feldt-Rasmussen B, Ortiz A, Bagi P, Sorensen CA, Morales E, and Porrini E

Abstract

Introduction: The pathogenesis of renal disease in obesity and metabolic syndrome (MS) is mostly unknown. This is in part because of the limited information about renal morphological changes in these conditions. We evaluated renal histology in subjects with MS and those without MS, who are participants in the European Nephrectomy Biobank (ENBiBA) project., Methods: MS was defined with at least 3 of the following criteria: (i) body mass index (BMI) ≥27 kg/m 2 ; (ii) prediabetes: fasting glucose of 100-125 mg/dl or HbA1c >5.7%; (iii) systolic or diastolic blood pressure >140/90 mm Hg or the use of medications; and (iv) triglycerides >150 mg/dl or high-density lipoprotein cholesterol <40 (in men) or 50 mg/dl (in women). The absence of these criteria defined patients without MS. Exclusion criteria were diabetes or known causes of renal disease., Results: A total of 157 cases were evaluated: 49 without and 108 with MS. Those with MS were older (54 ± 16 vs. 66 ± 11, P  < 0.0001), had more prevalent chronic kidney disease (CKD, estimated glomerular filtration rate [eGFR] <60 ml/min): 24% (23%) versus 4% (8%) ( P  = 0.02), and had higher albumin-to-creatinine ratio (10 [4-68] vs. 4.45 [0-27], P  = 0.05) than those without MS. Global sclerosis (3% [1-7] vs. 7% [3-13], P  < 0.0001), nodular sclerosis, mesangial expansion, glomerulomegaly; moderate + severe hyalinosis, and arteriosclerosis were more frequent in those with MS than in those without (88 [82] vs. 29 [59]; 83 [77] vs. 30 [61]; P  < 0.05). These vascular changes were independent of differences in age., Conclusion: In MS, ischemic renal disease may play a role in renal disease. In addition, some patients may develop lesions compatible with diabetic nephropathy such as increased mesangial expansion and nodular sclerosis. Further analyses are needed to study the consequences of the pandemic of obesity on renal health., (© 2024 Published by Elsevier, Inc., on behalf of the International Society of Nephrology.)

Published
2024
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