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Mesno koštano brašno dobiveno od životinjskih nusproizvoda podrijetlom od kopnenih sisavaca, peradi ili riba zbog svog dobrog aminokiselinskog sastava često se koristilo kao dodatak krmnim smjesama. Pojavom goveđe spongiformne encefalopatije i njenim dokazanim širenjem putem hrane koja sadrži životinjske bjelančevine, uporaba mesnog koštanog brašna za hranidbu životinja je najprije ograničena 1994. godine, a zatim i sasvim zabranjena 2001. godine. Statistički podaci pokazuju da je totalnom zabranom uporabe mesnog koštanog brašna u ishrani životinja pojavnost goveđe spongiformne encefalopatije značajno pala. Međutim postavljaju se pitanja: da li mesno koštano brašno treba zanemariti kao kvalitetnu sirovinu ako se njime izbjegava hranjenje istovrsnih životinja i da li uvođenjem mesnog koštanog brašna riskiramo pojavu novih oblika transmisivne spongiformne encefalopatije?, Meat and bone meal derived from animal by-products originating from terrestrial mammals, poultry or fish because of its good amino acid composition was often used as a supplement to feed mixtures. With the advent of bovine spongiform encephalopathy and its proven spread through food that contains animal protein, the use of meat and bone meat in animal feeds was initially limited in 1994, and then completely prohibited in 2001. Statistical data show that a total feed ban on using meat and bone meal in animal nutrition significantly decreased bovine spongiform encephalopathy incidence. But the question is: should the meat and bone meal be ignored as a good quality raw material if one avoids feeding the same animal species and with the introduction of meat and bone meal do we risk the appearance of new forms of transmissible spongiform encephalopathy?

Životinjske bjelančevine, dobiveni od termički obrađenih životinjskih nusproizvoda podrijetlom od kopnenih sisavaca, peradi ili riba, zbog svoje hranjive vrijednosti, često se koriste kao dodatak krmnim smjesama. Sitne strukture nekih organa vidljive su mikroskopski pod različitim povećanjima. Mikroskopski u krmivima možemo identificirati dijelove kosti, mišića, hrskavice, dlake, perje, ljuske od jaja, riblje ljuske i ligamente. Dijelove mekih tkiva i kože najčešće ne možemo identificirati zbog termičke obrade u kafilerijama. Uvođenje mikroskopske metode u rutinsku laboratorijsku pretragu za identifikaciju životinjskih tkiva u krmivima, nužna je zbog bolesti goveđe spongiformne encefalopatije (GSE) i njene povezanosti s uporabom i hranidbom životinja životinjskim bjelančevinama., Additional animal proteins in feeds because of their edibility, is by adding ground slaughter by-products originating either from ruminants, poultry or fish. This means that fine structures are visible after microscopic inspection at different magnification. The principal particles of animal origin that might be present in feeds are bones, muscle fibres, cartilage, hairs, feather filaments, egg shells, fish scales and ligaments. Parts from organs, skin and other soft tissues are generally absent, because of their denaturation after sterilisation. The need of this identification is based on the prohibition on adding animal proteins to feeds intended for farm animals therefore a connection between appearance of Bovine spongiform encephalopathy (BSE) and feeding animals with animal proteins.