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Resume Les auteurs rapportent un cas complexe associant une leucemie lymphoide chronique, un leiomyoblastome digestif et une vascularite cutanee thrombosante avec anticorps anticardiolipine serique faisant discuter un nouveau mecanisme physiopathogenique des vascularites au cours des hemopathies.

The authors report a complex case in which chronic lymphoid leukaemia was associated with leiomyoblastoma of the digestive tract and cutaneous thrombosing vasculitis with serum anti-cardiolipin antibodies. They discuss a new physiopathogenetic mechanism of vasculitis in blood diseases.

An hemophagocytic syndrome occured in 3 patients with active Lupus Erythematosus. None of them exhibited any evidence of infectious pathology. Steroid therapy was effective. Relapse was observed in 2 patients and again resolved under steroid therapy. Moderate levels of TNF were observed in the 3 patients. Lupus must be considered as a possible cause of hemophagocytic syndrome in the absence of underlying infection.

Eclampsia and preeclampsia are still a frightening diagnosis for mothers and infants. We retrospectively studied the vascular and obstetrical prognosis in 55 pregnant women hospitalized for eclampsia or preeclampsia in an intensive care unit. Permanent hypertension persisted in 29% women after delivery. Gravidic hypertension reccure in 28% of subsequent pregnancies. There were no differences between the groups of eclamptic and preeclamptic women.

HELLP syndrome is a severe complication of gravidic arterial hypertension. We retrospectively studied prognostic factors of 87 eclampsia or preeclampsia with or without HELLP syndrome. The HELLP syndrome is an important factor of prognosis in gravidic hypertension.

The association between thrombocytopenic thrombotic purpura (TTP) and infectious or multisystem disease, pregnancy, transplantation, drugs and toxins is well known. The onset of TTP in the course of neoplasm is rarely described : only 7 cases have been reported (5 cases of gastric adenocarcinoma, 1 case of breast carcinoma and 1 case of carcinoma with unknown primary site). The authors report the first case of TTP associated with prostatic tumor.