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Start Over Author "J.P. Dommergues" Journal la revue de medecine interne
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1. Un syndrome d'activation histio-monocytaire peut révéler une maladie lupique. À propos de trois observations

Author

G. Tchernia, F. Brivet, J.P. Dommergues, C. Wallon, F Mielot, P. Colson, F. Boue, Gérard Tertian, and Jean-François Delfraissy

Subjects
Lupus erythematosus, Systemic lupus erythematosus, business.industry, Gastroenterology, medicine.disease, Underlying infection, Steroid therapy, immune system diseases, Immunology, Internal Medicine, medicine, Tumor necrosis factor alpha, skin and connective tissue diseases, business
Abstract

An hemophagocytic syndrome occured in 3 patients with active Lupus Erythematosus. None of them exhibited any evidence of infectious pathology. Steroid therapy was effective. Relapse was observed in 2 patients and again resolved under steroid therapy. Moderate levels of TNF were observed in the 3 patients. Lupus must be considered as a possible cause of hemophagocytic syndrome in the absence of underlying infection.

Published
1991
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