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Your search keyword '"Abolhasani, Milad"' showing total 12 results
Start Over Author "Abolhasani, Milad" Journal lab on a chip
12 results on '"Abolhasani, Milad"'

11. Shaken, and stirred: oscillatory segmented flow for controlled size-evolution of colloidal nanomaterials.

Author

Abolhasani, Milad, Oskooei, Ali, Klinkova, Anna, Kumacheva, Eugenia, and Günther, Axel

Subjects
*NANOSTRUCTURED materials, *MICROFLUIDICS, *NANOTECHNOLOGY, *FLUIDICS, *GOLD
Abstract

We introduce oscillatory segmented flow as a compact microfluidic format that accommodates slow chemical reactions for the solution-phase processing of colloidal nanomaterials. The strategy allows the reaction progress to be monitored at a dynamic range of up to 80 decibels (i.e., residence times of up to one day, equivalent to 720–14 400 times the mixing time) from only one sensing location. A train of alternating gas bubbles and liquid reaction compartments (segmented flow) was initially formed, stopped and then subjected to a consistent back-and-forth motion. The oscillatory segmented flow was obtained by periodically manipulating the pressures at the device inlet and outlet via square wave signals generated by non-wetted solenoid valves. The readily implementable format significantly reduced the device footprint as compared with continuous segmented flow. We investigated mixing enhancement for varying liquid segment lengths, oscillation amplitudes and oscillation frequencies. The etching of gold nanorods served as a case study to illustrate the utility of the approach for dynamic characterization and precise control of colloidal nanomaterial size and shape for 5 h. Oscillatory segmented flows will be beneficial for a broad range of lab-on-a-chip applications that require long processing times. [ABSTRACT FROM AUTHOR]

Published
2014
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12. Oscillatory multiphase flow strategy for chemistry and biology

Author

Milad Abolhasani, Klavs F. Jensen, Massachusetts Institute of Technology. Department of Chemical Engineering, Abolhasani, Milad, and Jensen, Klavs F

Subjects
Biomedical Engineering, Bioengineering, 02 engineering and technology, Biology, 010402 general chemistry, 01 natural sciences, Biochemistry, CHEMISTRY METHODS, Humans, Process engineering, Mixing (physics), business.industry, Chemistry, Multiphase flow, Control engineering, General Chemistry, 021001 nanoscience & nanotechnology, Clinical method, 0104 chemical sciences, Models, Chemical, Chemistry, Clinical, Pulsatile Flow, Current (fluid), Rheology, 0210 nano-technology, business
Abstract

Continuous multiphase flow strategies are commonly employed for high-throughput parameter screening of physical, chemical, and biological processes as well as continuous preparation of a wide range of fine chemicals and micro/nano particles with processing times up to 10 min. The inter-dependency of mixing and residence times, and their direct correlation with reactor length have limited the adaptation of multiphase flow strategies for studies of processes with relatively long processing times (0.5–24 h). In this frontier article, we describe an oscillatory multiphase flow strategy to decouple mixing and residence times and enable investigation of longer timescale experiments than typically feasible with conventional continuous multiphase flow approaches. We review current oscillatory multiphase flow technologies, provide an overview of the advancements of this relatively new strategy in chemistry and biology, and close with a perspective on future opportunities., Natural Sciences and Engineering Research Council of Canada (Postgraduate Fellowship)

Published
2016

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