1. Associations Between Inflammatory Markers, Hemostatic Markers, and Microvascular Complications in 182 Chinese Patients With Type 2 Diabetes Mellitus
- Author
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Nengneng Zheng, Xinping Shi, Xiongwei Chen, and Wen Lv
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Antithrombin III ,Clinical Biochemistry ,Fibrinogen ,Gastroenterology ,Statistics, Nonparametric ,chemistry.chemical_compound ,Asian People ,Von Willebrand factor ,Internal medicine ,Diabetes mellitus ,Plasminogen Activator Inhibitor 1 ,von Willebrand Factor ,Fibrinolysis ,medicine ,Humans ,Aged ,Disseminated intravascular coagulation ,biology ,Interleukin-6 ,business.industry ,Biochemistry (medical) ,C-reactive protein ,Type 2 Diabetes Mellitus ,Factor VII ,Middle Aged ,medicine.disease ,C-Reactive Protein ,Diabetes Mellitus, Type 2 ,chemistry ,Plasminogen activator inhibitor-1 ,Immunology ,biology.protein ,Regression Analysis ,Female ,Endothelium, Vascular ,business ,medicine.drug - Abstract
Objective : To examine the associations between inflammatory markers, coagulation and fibrinolysis parameters, and microvascular complications in 182 Chinese patients with type 2 diabetes mellitus (T2DM) who sought treatment at a large hospital in Zhejiang province, China. Methods : We investigated the relationships of blood inflammatory markers with hemostatic markers in 87 patients with T2DM who did not have complications and 95 patients with T2DM who had microvascular complications. Results : C-reactive protein (CRP) and interleukin-6 (IL-6) were significantly correlated with fibrinogen, thrombin–antithrombin III complex (TAT III), plasminogen activator inhibitor-1 (PAI-1), von Willebrand factor (vWF), and coagulation factors (F) VII in patients with T2DM who had microvascular complications ( P
- Published
- 2015