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The various forms of bronchoplastic and angioplastic procedures are the best means of avoiding pneumonectomy. Essential indications are limited respiratory reserve and central site of a malignancy. In a retrospective study 248 broncho- and angioplastic operations carried out in the years 1973 to 1983 were analyzed. Reference date for the analysis of survival was January 1986. In consequence the minimum period of follow-up was two years. For all patients (n = 248) the 5-year-survival was 22% with a 30-day-lethality of 13%. The 5-year-survival of all bronchial sleeve resections operated radically (stage I and II of the TNM-classification) (n = 44) was 42% with a 30-day-lethality of 7%. The 5-year-survival of all bronchoplastic operations of stage I and II (n = 88) was 38% with a 30-day-lethality of 14%. Improved suture material and surgical techniques caused a reduction of operative lethality from 23% to 8% during the described period. In the first thirty postoperative days the following complications caused death: Hemoptysis (n = 5), insufficiency of the anastomosis (n = 3), right heart failure (n = 5), pulmonary embolism (n = 4) and sepsis (n = 1).

4--9 years after transduodenal papillotomy an endoscopic-manometric and clinical control of the surgical result was done in 49 patients. The pressure difference of common bile duct and duodenum was of great interest. There existed a correlation between the pressure difference and other parameters so far, as air was frequently seen in those patients without pressure gradient between common bile duct and duodenum. Pathological activity of gamma-GT and a decrease of Prothrombine-time was found after a high pressure difference. It may be possible that anatomical variations of the biliary system and the duodenum have some importance for the formation of stones.

Two different experimental procedures were used to induce pancreatitis in rats: distal ligature of the common bile duct and the Pfeffer method in modification of Nevalainen. It could be shown that consumption of complement can be demonstrated even in pancreatitis induced by other than immunological models. Further examination in decomplemented rats showed the possibility of inducing acute pancreatitis by the above-mentioned models, although of less intensity. Therefore, the complement system will be an important factor for the progress and intensity of the inflammation process.

Over the last decades the medical and social importance of bronchial carcinoma has increased because of its incidence and poor prognosis. Until recently only surgery has offered the chance of a cure for non-small-cell lung cancer with a 5-year-survival of 25%. Today with the development of tissue-sparing techniques curative treatment is accessible also to patients with limited lung function and centrally located tumors.

56 Patienten mit 5–11 Jahre zuruckliegender Papillenplastik wurden hinsichtlich ihrer Spatergebnisse nachuntersucht. Die Nachuntersuchung beinhaltete Laboruntersuchungen leberspezifischer Parameter, eine Gallenleeraufnahme, eine endoskopisch-retrograde Cholangiographie als auch in 34 Fallen eine manometrische Untersuchung der Druckverhaltnisse im System Gallenwege Duodenum. Die subjektiven Ergebnisse waren zufriedenstellend. Die Laboruntersuchungen ergaben keine Hinweise fur eine Cholangitis. Die ERC und Manometrie zeigten ebenfalls den gunstigen Effekt der Papillotomie in der Behandlung von Galleabflusstorungen.