1. Optically Detected Degradation of NaYF4:Yb,Tm-Based Upconversion Nanoparticles in Phosphate Buffered Saline Solution
- Author
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Blaž Belec, Ute Resch-Genger, Marco Kraft, Maja Ponikvar-Svet, Janez Kovač, Darja Lisjak, Christian Würth, and Olivija Plohl
- Subjects
Materials science ,Inorganic chemistry ,Potentiometric titration ,Nanoparticle ,02 engineering and technology ,Surfaces and Interfaces ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Fluorescence ,Photon upconversion ,0104 chemical sciences ,chemistry.chemical_compound ,X-ray photoelectron spectroscopy ,chemistry ,Electrochemistry ,General Materials Science ,0210 nano-technology ,Luminescence ,Dissolution ,Fluoride ,Spectroscopy - Abstract
In a proof-of-concept study, we assessed different analytical and spectroscopic parameters for stability screening of differently sized β-NaYF4:20 mol % Yb3+, 2 mol % Tm3+ upconversion nanoparticles (UCNPs) exemplarily in the bioanalytically relevant buffer phosphate buffered saline (PBS; pH 7.4) at 37 and 50 °C. This included the potentiometric determination of the amount of released fluoride ions, surface analysis with X-ray photoelectron spectroscopy (XPS), and steady-state and time-resolved fluorescence measurements. Based on these results, the luminescence lifetime of the 800 nm upconversion emission was identified as an optimum parameter for stability screening of UCNPs and changes in particle surface chemistry.
- Published
- 2017