1. Unraveling Interactions between Ionic Liquids and Phospholipid Vesicles Using Nanoplasmonic Sensing
- Author
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Joanna Witos, Suvi-Katriina Ruokonen, Giacomo Russo, and Susanne K. Wiedmer
- Subjects
Inorganic chemistry ,Ionic Liquids ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,chemistry.chemical_compound ,Biomimetic Materials ,Electrochemistry ,Nanotechnology ,General Materials Science ,Phosphonium ,Lipid bilayer ,Spectroscopy ,Phospholipids ,Unilamellar Liposomes ,Titanium ,Vesicle ,Substrate (chemistry) ,Surfaces and Interfaces ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,0104 chemical sciences ,chemistry ,Chemical engineering ,Silicon nitride ,Sodium hydroxide ,Ionic liquid ,Titanium dioxide ,Phosphatidylcholines ,0210 nano-technology - Abstract
Owing to their unique properties and unlimited structural combinations, the ubiquitous use of ionic liquids (ILs) is steadily increasing. The objective of the present work is to shed light onto the effects of amidinium- and phosphonium-based ILs on phospholipid vesicles using a nanoplasmonic sensing measurement technique. A new and relatively simple method was developed for the immobilization of large unilamellar vesicles on two different hydrophilic surfaces composed of titanium dioxide and silicon nitride nanolayers. Among the pretreatment conditions studied, vesicle attachment on both substrate materials was achieved with HEPES buffer in the presence of sodium hydroxide and calcium chloride. To get an understanding of how ILs interact with intact vesicles or with supported lipid bilayers, the ILs 1,5-diazabicyclo(4.3.0)non-5-enium acetate ([DBNH][OAc]), tributyl(tetradecyl)phosphonium acetate ([P14444][OAc]), and tributylmethylphosphonium acetate ([P4441][OAc]) were introduced into the biomimetic syste...
- Published
- 2017