1. Effect of low-level light therapy before radiotherapy in oral squamous cell carcinoma: An in vitro study
- Author
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Angeliny Tamiarana Lima Tabosa, Marcela Gonçalves Souza, Sabrina Ferreira de Jesus, Danielle Ferreira Rocha, Lorena dos Reis Pereira Queiroz, Eloá Mangabeira Santos, Victor Hugo Dantas Guimarães, Luciano Alves de Araújo Andrade, Sérgio Henrique Santos, Alfredo Maurício Batista de Paula, Paulo Eduardo Narcizo de Souza, Lucyana Conceição Farias, and André Luiz Sena Guimarães
- Subjects
Squamous Cell Carcinoma of Head and Neck ,Head and Neck Neoplasms ,Carcinoma, Squamous Cell ,Humans ,Surgery ,Mouth Neoplasms ,Dermatology ,Low-Level Light Therapy ,Reactive Oxygen Species - Abstract
Radiation therapy for head and neck squamous cell carcinoma (HNSCC) is associated with several complications. Although photobiomodulation (PBM) has radioprotective effects in normal tissue, it could also enhance the growth of neoplastic cells. Thus, the present study aimed to investigate the cellular response of oral squamous cell carcinoma with pre-exposure to low-level phototherapy before radiotherapy. SCC9, Cal-27, A431, and HaCaT cell lines were subjected to low-level light therapy and radiotherapy. The cells were treated with a single energy density (300 J/cm
- Published
- 2022