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Your search keyword '"Véronique Mansat-De Mas"' showing total 2 results
Start Over Author "Véronique Mansat-De Mas" Journal leukemialymphoma
2 results on '"Véronique Mansat-De Mas"'

1. More than ten percent of relapses occur after five years in AML patients with

Author

Sarah, Bertoli, Suzanne, Tavitian, Emilie, Bérard, Véronique, Mansat-De Mas, Laetitia, Largeaud, Noémie, Gadaud, Jean-Baptiste, Rieu, François, Vergez, Isabelle, Luquet, Françoise, Huguet, Audrey, Sarry, Eric, Delabesse, and Christian, Récher

Subjects
Leukemia, Myeloid, Acute, Mutation, Humans, Nuclear Proteins, Neoplasm Recurrence, Local, Nucleophosmin
Published
2020

2. Chronic myeloid leukemia associated with B-cell chronic lymphocytic leukemia: evidence of two separate clones as shown by combined cell-sorting and fluorescence in situ hybridisation

Author

Emilienne Kuhlein, Véronique Mansat-De Mas, Guy Laurent, Georges Cassar, Françoise Rigal-Huguet, and Nicole Dastugue

Subjects
Male, Cancer Research, Chronic lymphocytic leukemia, Antigens, CD19, Fusion Proteins, bcr-abl, CD19, Fusion gene, Neoplasms, Multiple Primary, hemic and lymphatic diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, Humans, neoplasms, In Situ Hybridization, Fluorescence, Aged, CD20, B-Lymphocytes, ABL, biology, Myeloid leukemia, Hematology, DNA, Neoplasm, medicine.disease, Flow Cytometry, Neoplastic Cells, Circulating, Virology, Molecular biology, Leukemia, Lymphocytic, Chronic, B-Cell, Clone Cells, Cell Transformation, Neoplastic, Oncology, biology.protein, Stem cell, K562 cells
Abstract

The simultaneous occurrence of Philadelphia positive chronic myeloid leukemia (Ph+ CML) and B-cell chronic lymphocytic leukemia (B-CLL) is a rare event which raises the possibility that the two malignant clones derive from a common, or distinct, malignant stem cells. In this study, we used combined CD19-based cell-sorting and fluorescence in situ hybridisation (FISH) to investigate whether or not the BCR-ABL fusion gene was present in the malignant B-cells of a patient who presented a Ph+ CML/B-CLL association. The CD19+ cells lacked the BCR-ABL rearrangement whereas all CD19-cells exhibited the fusion gene. This result demonstrates that B-cell transformation occurred in a Ph-B-cell subset.

Published
2003

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