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Start Over Author "Boarino, V" Journal liver transplantation official publication of the american association for the study of liver diseases and the international liver transplantation society
2 results on '"Boarino, V"'

1. Management of biliary anastomotic strictures after liver transplantation (BASALT study): A nationwide Italian survey.

Author

Cantù P, Parzanese I, Balassone V, Di Sario A, Soggiu F, Lombardi G, Barbaro F, Pisani A, Baldan A, Cariani G, Boarino V, Fasoli A, Bertani H, Forti E, Bulajic M, Ghinolfi D, Nadal E, Cerofolini A, Barresi L, Catalano G, Stroppa I, Traini S, Mazzaferro V, Cipolletta L, Tringali A, Costamagna G, Ravelli P, Bazzoli F, Merighi A, Parodi MC, Conigliaro R, Mutignani M, Zilli M, Filipponi F, Fantin A, Rodella L, Tarantino I, Traina M, Salizzoni M, Rosa R, Malinverno F, Invernizzi F, Manini MA, Donato MF, Colombo M, Conte D, Rossi G, and Penagini R

Subjects
Bile Ducts diagnostic imaging, Bile Ducts pathology, Cholangiopancreatography, Endoscopic Retrograde instrumentation, Cholangiopancreatography, Endoscopic Retrograde methods, Cholestasis diagnostic imaging, Cholestasis etiology, Constriction, Pathologic diagnostic imaging, Constriction, Pathologic etiology, Follow-Up Studies, Hospitals, High-Volume statistics & numerical data, Humans, Italy, Magnetic Resonance Angiography, Patient Selection, Postoperative Complications diagnostic imaging, Postoperative Complications etiology, Retrospective Studies, Stents, Surveys and Questionnaires, Treatment Outcome, Bile Ducts surgery, Cholangiopancreatography, Endoscopic Retrograde statistics & numerical data, Cholestasis surgery, Constriction, Pathologic surgery, Liver Transplantation adverse effects, Postoperative Complications surgery
Published
2017
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2. Predominance of pre-S1 mutated hepatitis B virus in a patient following treatment with adefovir dipivoxil.

Author

Villa E, Boarino V, Grottola A, Gelmini R, and Lama NG

Subjects
Drug Resistance, Microbial, Gene Deletion, Hepatitis B virus physiology, Humans, Lamivudine therapeutic use, Male, Reverse Transcriptase Inhibitors therapeutic use, Salvage Therapy, Adenine analogs & derivatives, Adenine therapeutic use, Antiviral Agents therapeutic use, Hepatitis B Surface Antigens genetics, Hepatitis B virus drug effects, Hepatitis B virus genetics, Mutation, Organophosphonates, Protein Precursors genetics
Abstract

A liver transplant recipient reinfected with a lamivudine-resistant mixed wild-type/pre-S1-deleted hepatitis B virus (HBV) strain and rescued with adefovir dipivoxil was still HBV DNA positive after more than 1 year of therapy. Analysis of serum HBV DNA, amplified by polymerase chain reaction and directly sequenced by dideoxy nucleotide chain-termination method, showed that adefovir inhibited the wild type, but not the pre-S1-deleted HBV. Predominance of the pre-S1-deleted strain over wild type after adefovir treatment suggests that either adefovir inhibited the wild type more effectively or the pre-S1 mutant replicates more efficiently. The normality of liver condition confirms that to exert its pathogenic effect, the pre-S1-deleted strain requires the presence of wild-type virus.

Published
2003
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