1. Nanostructured luminescently labeled nucleic acids
- Author
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Jason Y. Park, Larry J. Kricka, and Paolo Fortina
- Subjects
Copper nanoclusters ,Biophysics ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,Combinatorial chemistry ,0104 chemical sciences ,law.invention ,Nanoclusters ,chemistry.chemical_compound ,chemistry ,Chemistry (miscellaneous) ,law ,Nucleic acid ,Electrochemiluminescence ,0210 nano-technology ,Luminescence ,DNA ,Chemiluminescence - Abstract
Important and emerging trends at the interface of luminescence, nucleic acids and nanotechnology are: (i) the conventional luminescence labeling of nucleic acid nanostructures (e.g. DNA tetrahedron); (ii) the labeling of bulk nucleic acids (e.g. single-stranded DNA, double-stranded DNA) with nanostructured luminescent labels (e.g. copper nanoclusters); and (iii) the labeling of nucleic acid nanostructures (e.g. origami DNA) with nanostructured luminescent labels (e.g. silver nanoclusters). This review surveys recent advances in these three different approaches to the generation of nanostructured luminescently labeled nucleic acids, and includes both direct and indirect labeling methods.
- Published
- 2016