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Start Over Author "Yang, Qi-Hua" Journal main group chemistry
2 results on '"Yang, Qi-Hua"'

2. Synthesis, anti-gastric cancer activity and docking studies of naphthol derivatives.

Author

Shao, Hua, Kong, Cui, Yang, Qi-Hua, and Tai, Qing-Pin

Subjects
X-ray crystallography, MOLECULAR docking, SINGLE crystals, STOMACH cancer, CANCER cells
Abstract

The synthesis and characterization of six novel naphthol derivatives (1–6) were realized by means of IR, 1H NMR, HRMS and single crystal X-ray crystallography. The anticancer activities of these compounds were investigated against three human gastric cancer cells (MGC-803, SGC-790, MKN45) by MTT assay. In addition, the relationship between anticancer activity and structure of compounds (1–3) was further investigated through molecular docking study. [ABSTRACT FROM AUTHOR]

Published
2019
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