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Hot deformation behaviors of an antibacterial 50Cr15MoVCu tool steel were studied. The flow stress curves presented three typical characteristics: (i) a single peak dynamic recrystallization curve, (ii) a monotone incremental work-hardening curve, and (iii) the equilibrium dynamic recovery curve. The flow stress increased with the increase of the deformation rate at each deformation temperature and decreased with the increase of the deformation temperature at the same deformation rate. The thermal activation energy and material constants were Q of 461.6574 kJ/mol, A of 3.42 × 1017, and α of 0.00681 MPa−1, respectively. The high temperature constitutive equation was: Z = ε ˙ exp Q / RT = 3 . 42   ×   10 17 sinh 0. 0068   ×   σ 5. 6807 . Based on the processing maps and microstructure evolution, the best hot working process was a deformation temperature of 1050 °C and deformation rate of 0.001 s−1. [ABSTRACT FROM AUTHOR]