1. Fe-doped brushite bone cements with antibacterial property
- Author
-
Liu Xinping, Li Xiaoyu, Santuan Zhao, Guangda Li, Zhang Nan, Jing Aihua, Tian Zhang, and Zhang Kaili
- Subjects
Antibacterial property ,Materials science ,Mechanical Engineering ,technology, industry, and agriculture ,chemistry.chemical_element ,02 engineering and technology ,Calcium ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Microstructure ,01 natural sciences ,0104 chemical sciences ,chemistry ,Mechanics of Materials ,Fe doped ,Iron content ,Setting time ,General Materials Science ,Brushite ,Iron phosphate ,0210 nano-technology ,Nuclear chemistry - Abstract
In present research, Fe-doped brushite bone cements were synthesized. The setting time, microstructure and antibacterial property of samples were investigated. The results showed that the setting time of cements was retarded to about 20 min and 123 min, respectively, as iron doping content increasing from 1 mol% to 5 mol% in β-TCP powder. Moreover, Fe-doped cements had much bigger crystal particles and calcium iron phosphate was identified in them. Furthermore, Fe-doped cements performed well in inhibiting the growth of Staphylococcus aureus and Pseudomonas aeruginosa, and larger inhibition halo was obtained with more iron content. Nevertheless, the Fe-loaded cements were not so sensitive to Escherichia coli as to the other two bacteria.
- Published
- 2018