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A component with multiple weak sites is widely used in practical engineering and the existence of multiple weak sites can significantly decrease the component reliability. On the other hand, only a few components bear static loading and most components bear dynamic loading. In this paper, a reliability model of isomorphic component with multiple weak sites is built based on an order statistics model and the influences of strength decentrality and loading decentrality on isomorphic component with multiple weak sites are discussed. Furthermore the influence of loading times is studied in detail. The results show that unlike a component with only one weak site, not only does the failure of a component with multiple weak sites have a relationship with the safety margin, but there also exist relationships with the number of weak sites, the loading roughness, and loading times. he work in this paper is of some guiding significance in reliability design and assessment of a component with multiple weak sites under complex loading. [ABSTRACT FROM AUTHOR]