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This paper discusses statistical inference and optimal design of constant-stress accelerated life testing for the Chen distribution under progressive Type-II censoring. The scale parameter of the life distribution is assumed to be a logarithmic linear function of the stress level. The maximum likelihood estimates of the parameters are obtained. Then, the observed Fisher information matrix is derived and utilized to construct asymptotic confidence intervals. Meanwhile, the parametric bootstrap methods are provided for the interval estimation. In addition, the Bayes estimates under the squared error loss function are obtained by applying the Tierney and Kadane technique and Lindley's approximation. As for the optimal design, D- and A-optimality criteria are considered to determine the optimal transformed stress level. Finally, the simulation is carried out to demonstrate the proposed estimation techniques and the optimal criteria, and a real data set is discussed. [ABSTRACT FROM AUTHOR]