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In recent years, deep learning has been successfully applied to medical image analysis and provided assistance to medical professionals. Machine learning is being used to offer diagnosis suggestions, identify regions of interest in images, or augment data to remove noise. Training models for such tasks require a large amount of labeled data. It is often difficult to procure such data due to the fact that these requires experts to manually label them, in addition to the privacy and legal concerns that limiting their collection. Due to this, creating self-supervision learning methods and domain-adaptation techniques dedicated to this domain is essential. This paper reviews concepts from the field of deep learning and how they have been applied to medical image analysis. We also review the current state of self-supervised learning methods and their applications to medical images. In doing so, we will also present the resource ecosystem of researchers in this field, such as datasets, evaluation methodologies, and benchmarks. [ABSTRACT FROM AUTHOR]

Data normalization is a data preprocessing task and one of the first to be performed during intellectual analysis, particularly in the case of tabular data. The importance of its implementation is determined by the need to reduce the sensitivity of the artificial intelligence model to the values of the features in the dataset to increase the studied model's adequacy. This paper focuses on the problem of effectively preprocessing data to improve the accuracy of intellectual analysis in the case of performing medical diagnostic tasks. We developed a new two-step method for data normalization of numerical medical datasets. It is based on the possibility of considering both the interdependencies between the features of each observation from the dataset and their absolute values to improve the accuracy when performing medical data mining tasks. We describe and substantiate each step of the algorithmic implementation of the method. We also visualize the results of the proposed method. The proposed method was modeled using six different machine learning methods based on decision trees when performing binary and multiclass classification tasks. We used six real-world, freely available medical datasets with different numbers of vectors, attributes, and classes to conduct experiments. A comparison between the effectiveness of the developed method and that of five existing data normalization methods was carried out. It was experimentally established that the developed method increases the accuracy of the Decision Tree and Extra Trees Classifier by 1–5% in the case of performing the binary classification task and the accuracy of the Bagging, Decision Tree, and Extra Trees Classifier by 1–6% in the case of performing the multiclass classification task. Increasing the accuracy of these classifiers only by using the new data normalization method satisfies all the prerequisites for its application in practice when performing various medical data mining tasks. [ABSTRACT FROM AUTHOR]

Today, artificial intelligence (AI) and machine learning (ML) have dramatically advanced in various industries, especially medicine. AI describes computational programs that mimic and simulate human intelligence, for example, a person's behavior in solving problems or his ability for learning. Furthermore, ML is a subset of artificial intelligence. It extracts patterns from raw data automatically. The purpose of this paper is to help researchers gain a proper understanding of machine learning and its applications in healthcare. In this paper, we first present a classification of machine learning-based schemes in healthcare. According to our proposed taxonomy, machine learning-based schemes in healthcare are categorized based on data pre-processing methods (data cleaning methods, data reduction methods), learning methods (unsupervised learning, supervised learning, semi-supervised learning, and reinforcement learning), evaluation methods (simulation-based evaluation and practical implementation-based evaluation in real environment) and applications (diagnosis, treatment). According to our proposed classification, we review some studies presented in machine learning applications for healthcare. We believe that this review paper helps researchers to familiarize themselves with the newest research on ML applications in medicine, recognize their challenges and limitations in this area, and identify future research directions. [ABSTRACT FROM AUTHOR]

Machine learning in the medical area has become a very important requirement. The healthcare professional needs useful tools to diagnose medical illnesses. Classifiers are important to provide tools that can be useful to the health professional for this purpose. However, questions arise: which classifier to use? What metrics are appropriate to measure the performance of the classifier? How to determine a good distribution of the data so that the classifier does not bias the medical patterns to be classified in a particular class? Then most important question: does a classifier perform well for a particular disease? This paper will present some answers to the questions mentioned above, making use of classification algorithms widely used in machine learning research with datasets relating to medical illnesses under the supervised learning scheme. In addition to state-of-the-art algorithms in pattern classification, we introduce a novelty: the use of meta-learning to determine, a priori, which classifier would be the ideal for a specific dataset. The results obtained show numerically and statistically that there are reliable classifiers to suggest medical diagnoses. In addition, we provide some insights about the expected performance of classifiers for such a task. [ABSTRACT FROM AUTHOR]

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of different types of diseases and their tissue status. These images are an essential resource with which to define biological compositions or analyze cell and tissue structures. This imaging modality is very important for diagnostic applications. The analysis of histopathology images is a prolific and relevant research area supporting disease diagnosis. In this paper, the challenges of histopathology image analysis are evaluated. An extensive review of conventional and deep learning techniques which have been applied in histological image analyses is presented. This review summarizes many current datasets and highlights important challenges and constraints with recent deep learning techniques, alongside possible future research avenues. Despite the progress made in this research area so far, it is still a significant area of open research because of the variety of imaging techniques and disease-specific characteristics. [ABSTRACT FROM AUTHOR]