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6 results on '"Trilling, Mirko"'

2. Analysis of the Long-Term Impact on Cellular Immunity in COVID-19-Recovered Individuals Reveals a Profound NKT Cell Impairment

Author

Liu, Jia, primary, Yang, Xuecheng, additional, Wang, Hua, additional, Li, Ziwei, additional, Deng, Hui, additional, Liu, Jing, additional, Xiong, Shue, additional, He, Junyi, additional, Feng, Xuemei, additional, Guo, Chunxia, additional, Wang, Weixian, additional, Zelinskyy, Gennadiy, additional, Trilling, Mirko, additional, Sutter, Kathrin, additional, Senff, Tina, additional, Menne, Christopher, additional, Timm, Joerg, additional, Zhang, Yanfang, additional, Deng, Fei, additional, Lu, Yinping, additional, Wu, Jun, additional, Lu, Mengji, additional, Yang, Dongliang, additional, Dittmer, Ulf, additional, Wang, Baoju, additional, and Zheng, Xin, additional

Published
2021
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3. Erratum for Westmeier et al., “Impaired Cytotoxic CD8 + T Cell Response in Elderly COVID-19 Patients”

Author

Westmeier, Jaana, primary, Paniskaki, Krystallenia, additional, Karaköse, Zehra, additional, Werner, Tanja, additional, Sutter, Kathrin, additional, Dolff, Sebastian, additional, Overbeck, Marvin, additional, Limmer, Andreas, additional, Liu, Jia, additional, Zheng, Xin, additional, Brenner, Thorsten, additional, Berger, Marc M., additional, Witzke, Oliver, additional, Trilling, Mirko, additional, Lu, Mengji, additional, Yang, Dongliang, additional, Babel, Nina, additional, Westhoff, Timm, additional, Dittmer, Ulf, additional, and Zelinskyy, Gennadiy, additional

Published
2020
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4. Impaired Cytotoxic CD8 + T Cell Response in Elderly COVID-19 Patients

Author

Westmeier, Jaana, primary, Paniskaki, Krystallenia, additional, Karaköse, Zehra, additional, Werner, Tanja, additional, Sutter, Kathrin, additional, Dolff, Sebastian, additional, Overbeck, Marvin, additional, Limmer, Andreas, additional, Liu, Jia, additional, Zheng, Xin, additional, Brenner, Thorsten, additional, Berger, Marc M., additional, Witzke, Oliver, additional, Trilling, Mirko, additional, Lu, Mengji, additional, Yang, Dongliang, additional, Babel, Nina, additional, Westhoff, Timm, additional, Dittmer, Ulf, additional, and Zelinskyy, Gennadiy, additional

Published
2020
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6. Impaired Cytotoxic CD8+T Cell Response in Elderly COVID-19 Patients

Author

Westmeier, Jaana, Paniskaki, Krystallenia, Karaköse, Zehra, Werner, Tanja, Sutter, Kathrin, Dolff, Sebastian, Overbeck, Marvin, Limmer, Andreas, Liu, Jia, Zheng, Xin, Brenner, Thorsten, Berger, Marc M., Witzke, Oliver, Trilling, Mirko, Lu, Mengji, Yang, Dongliang, Babel, Nina, Westhoff, Timm, Dittmer, Ulf, and Zelinskyy, Gennadiy

Abstract

Cytotoxic T cells are responsible for the elimination of infected cells and are key players in the control of viruses. CD8+T cells with an effector phenotype express cytotoxic molecules and are able to perform target cell killing. COVID-19 patients with a mild disease course were analyzed for the differentiation status and cytotoxic profile of CD8+T cells. SARS-CoV-2 infection induced a vigorous cytotoxic CD8+T cell response. However, this cytotoxic profile of T cells was not detected in COVID-19 patients over the age of 80 years. Thus, the absence of a cytotoxic response in elderly patients might be a possible reason for the more frequent severity of COVID-19 in this age group than in younger patients.

Published
2020
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