1. [Malaria severity criteria and prognostic factors among children in Dakar].
- Author
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Camara B, Diagne-Gueye NR, Faye PM, Fall ML, Ndiaye JL, Ba M, and Sow HD
- Subjects
- Adolescent, Age Factors, Anemia epidemiology, Anemia etiology, Child, Child, Preschool, Consciousness Disorders epidemiology, Consciousness Disorders etiology, Female, Hospitals, Pediatric statistics & numerical data, Humans, Hypoglycemia epidemiology, Hypoglycemia etiology, Infant, Malaria, Cerebral epidemiology, Malaria, Falciparum mortality, Male, Parasitemia epidemiology, Prognosis, Prospective Studies, Respiratory Insufficiency epidemiology, Respiratory Insufficiency etiology, Risk Factors, Seizures epidemiology, Seizures etiology, Senegal epidemiology, Severity of Illness Index, Malaria, Falciparum epidemiology
- Abstract
Introduction: Severity factors associated with malaria as well as prognostic factors for death were assessed at the Dakar Centre Hospitalier National d'Enfants Albert Royer de Fann (CHNEAR)., Patients and Methods: A prospective study was carried out from January 1 to December 31, 2007 involving children from 0 to 15 years of age, admitted for plasmodium falciparum malaria with positive thick drop examination, meeting at least one of the WHO 2000 malaria severity criteria. Acidosis was not studied., Outcome: The rate of severe malaria cases in our hospital was 6.4%. The sex ratio was 1.4 and the median age of patients at 91 months. A peak was observed during the 4th trimester (75.5%). Convulsions (52.5%) and obtundation (49.4%) were the most common signs of clinical severity while hyperparasitemia and severe anemia ranged at 27.2% and 21.6%, respectively. Lethality was 11.1% and the main death risk factors were young age (p = 0.025), coma (p = 0.007), respiratory distress (p = 0.04), or hypoglycemia (p = 0.001)., Conclusion: Reducing malaria hospital mortality in Senegal may be obtained by proper management of poor prognostic factors such as coma, respiratory distress, and hypoglycemia.
- Published
- 2011
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