Hypertension represents a risk factor for the cardiovascular diseases. Depending on the presence of a known etiology, hypertension is essential or secondary. In case of essential hypertension, lately there have been proposed several theories, such as genetic predisposition, lifestyle, and infectious etiology. The pathogens most commonly studied are Chlamydia pneumoniae, Cytomegalovirus, Helicobacter pylori and hepatitis A. Through endothelial dysfunction, molecular mimicry, the activation of renin-angiotensin-aldosterone system or some secreted substances, germs manage to induce changes, which may contribute to the onset of hypertension. Therefore prevention and proper treatment of infections may decrease the risk of developing cardiovascular diseases including hypertension. Correct treatment of hypertension involves, besides non-pharmacological and drug therapy, the identification of potential modifiable causes, such as renal artery fibromuscular dysplasia, pheochromocytoma, coarctation of the aorta and others. [ABSTRACT FROM AUTHOR]