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Yulia V Kotovskaya,1 Zhanna D Kobalava,1 Artemy V Orlov21Propedeutics Department, Peoples’ Friendship University of Russia, 2Competitive System Analysis Department (No 65), National Research Nuclear University MEPhI, Moscow, RussiaBackground: The objective of this study was to validate the novel integration of oscillometric (Vasotens®) technology into a BPLab® ambulatory blood pressure (BP) monitoring system to measure central BP, the aortic augmentation index, and pulse wave velocity (PWV) compared with the recommended and widely accepted tonometric method.Methods: The ARTERY Society guidelines for comparison of PWV measurement techniques were used as the basis for recruitment of 99 individuals (mean age 44±19 years, 52 males). The standard for comparison was the conventional “classic” SphygmoCor device.Results: Accordance of the two methods was satisfactory (r=0.98, mean difference of 2.9±3.5 mmHg for central systolic BP; r=0.98, mean difference of −1.1±2.3 mmHg for central diastolic BP; r=0.83, mean difference of −2.6%±13% for aortic augmentation index; r=0.85, mean difference of 0.69±1.4 for PWV).Conclusion: The performance of Vasotens algorithms using an oscillometric ambulatory BP monitoring system is feasible for accurate diagnosis, risk assessment, and evaluation of the effects of antihypertensive drugs.Keywords: validation study, ambulatory, 24-hour, monitoring, arterial stiffness, pulse wave velocity, augmentation index, central blood pressure