1. A 4×500mm2 cloverleaf detector system forin vivobone lead measurement
- Author
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David E.B. Fleming and Caitlin E. Mills
- Subjects
Reproducibility ,Materials science ,business.industry ,Detector ,X-ray detector ,X-ray fluorescence ,General Medicine ,Fluorescence ,Imaging phantom ,Nuclear magnetic resonance ,In vivo ,Calibration ,Nuclear medicine ,business - Abstract
A 4 × 500 mm 2 “cloverleaf” low energy germaniumdetector array has been assembled for the purpose of in vivo bone lead measurement through x-ray fluorescence. Using Cd 109 as an exciting source, results are reported from a leg phantom simulating measurement of lead in a human tibia. For high activity ( 4.0 – 4.4 GBq ) and low activity ( 0.18 – 0.19 GBq ) sources, measurement results are reported for both the cloverleaf system and a conventional single detector system of equivalent surface area ( 2000 mm 2 ) . The mean uncertainty and reproducibility of measurement were both significantly improved for the cloverleaf system with a high activity Cd 109 source. When using a source activity of 4.4 GBq , measurement of the phantom resulted in an average bone leaduncertainty of 0.79 μ g ∕ g and a reproducibility of 0.84 μ g ∕ g . These results represent the highest precision yet reported from a bone leadx-ray fluorescence system.
- Published
- 2007
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