1. The Effect of Preoperative Apolipoprotein A-I on the Prognosis of Surgical Renal Cell Carcinoma
- Author
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Guo, Shengjie, He, Xiaobo, Chen, Qian, Yang, Guangwei, Yao, Kai, Dong, Pei, Ye, Yunlin, Chen, Dong, Zhang, Zhiling, Qin, Zike, Liu, Zhuowei, Li, Zaishang, Xue, Yunfei, Zhang, Meng, Liu, Ruiwu, Zhou, Fangjian, and Han, Hui
- Subjects
Atherosclerosis ,Clinical Research ,Kidney Disease ,Cancer ,Adult ,Aged ,Apolipoprotein A-I ,Carcinoma ,Renal Cell ,Cohort Studies ,Female ,Follow-Up Studies ,Humans ,Kidney Neoplasms ,Lipids ,Male ,Middle Aged ,Neoplasm Staging ,Prognosis ,Reference Values ,Retrospective Studies ,Statistics as Topic ,Survival Rate ,Clinical Sciences ,Arthritis & Rheumatology - Abstract
The prognostic value of serum lipid-profile in renal cell cancer (RCC) remains unknown. The purpose of the study is to explore the association between the serum lipid-profile and RCC patients.The levels of preoperative serum lipid-profile (including cholesterol, triglycerides, high-density lipoprotein-cholesterol [HDL-C], low-density lipoprotein-cholesterol [LDL-C], apolipoprotein A-I [ApoA-I], and apolipoprotein B [ApoB]) were retrospectively performed in 786 patients with RCC. The cutoff values of the lipids were determined by the receiver-operating characteristic (ROC) curve analysis. Univariate and multivariate Cox regression analyses were performed to investigate the prognostic value of serum lipids in RCC.Combined ROC analysis and univariate and multivariate Cox regression analyses, for overall survival (OS), revealed patients with low ApoA-I (
- Published
- 2016