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Your search keyword '"Miranda-Filloy JA"' showing total 8 results
Start Over Author "Miranda-Filloy JA" Journal medicine
8 results on '"Miranda-Filloy JA"'

1. Systemic lupus erythematosus in northwestern Spain: a 20-year epidemiologic study.

Author

Alonso MD, Llorca J, Martinez-Vazquez F, Miranda-Filloy JA, Diaz de Teran T, Dierssen T, Vazquez-Rodriguez TR, Gomez-Acebo I, Blanco R, Gonzalez-Gay MA, Alonso, Maria D, Llorca, Javier, Martinez-Vazquez, Francisco, Miranda-Filloy, Jose A, Diaz de Teran, Teresa, Dierssen, Trinidad, Vazquez-Rodriguez, Tomas R, Gomez-Acebo, Ines, Blanco, Ricardo, and Gonzalez-Gay, Miguel A

Published
2011
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2. Relapses and recurrences in giant cell arteritis: a population-based study of patients with biopsy-proven disease from northwestern Spain.

Author

Martinez-Lado L, Calviño-Díaz C, Piñeiro A, Dierssen T, Vazquez-Rodriguez TR, Miranda-Filloy JA, Lopez-Diaz MJ, Blanco R, Llorca J, Gonzalez-Gay MA, Martinez-Lado, Luciana, Calviño-Díaz, Carolina, Piñeiro, Angela, Dierssen, Trinidad, Vazquez-Rodriguez, Tomas R, Miranda-Filloy, Jose A, Lopez-Diaz, Maria J, Blanco, Ricardo, Llorca, Javier, and Gonzalez-Gay, Miguel A

Published
2011
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3. Audiovestibular manifestations in patients with ankylosing spondylitis.

Author

Amor-Dorado JC, Barreira-Fernandez MP, Vazquez-Rodriguez TR, Gomez-Acebo I, Miranda-Filloy JA, Diaz de Teran T, Llorca J, Gonzalez-Gay MA, Amor-Dorado, Juan C, Barreira-Fernandez, Maria P, Vazquez-Rodriguez, Tomas R, Gomez-Acebo, Ines, Miranda-Filloy, Jose A, Diaz de Teran, Teresa, Llorca, Javier, and Gonzalez-Gay, Miguel A

Published
2011
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4. The high prevalence of subclinical atherosclerosis in patients with ankylosing spondylitis without clinically evident cardiovascular disease.

Author

Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Miranda-Filloy JA, Dierssen T, Vaqueiro I, Blanco R, Martin J, Llorca J, Gonzalez-Gay MA, Gonzalez-Juanatey, Carlos, Vazquez-Rodriguez, Tomas R, Miranda-Filloy, Jose A, Dierssen, Trinidad, Vaqueiro, Ines, Blanco, Ricardo, Martin, Javier, Llorca, Javier, and Gonzalez-Gay, Miguel A

Published
2009
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5. Strokes at time of disease diagnosis in a series of 287 patients with biopsy-proven giant cell arteritis.

Author

Gonzalez-Gay MA, Vazquez-Rodriguez TR, Gomez-Acebo I, Pego-Reigosa R, Lopez-Diaz MJ, Vazquez-Triñanes MC, Miranda-Filloy JA, Blanco R, Dierssen T, Gonzalez-Juanatey C, Llorca J, Gonzalez-Gay, Miguel A, Vazquez-Rodriguez, Tomas R, Gomez-Acebo, Ines, Pego-Reigosa, Robustiano, Lopez-Diaz, Maria J, Vazquez-Triñanes, Matilde C, Miranda-Filloy, Jose A, Blanco, Ricardo, and Dierssen, Trinidad

Published
2009
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8. Audiovestibular manifestations in patients with limited systemic sclerosis and centromere protein-B (CENP-B) antibodies.

Author

Amor-Dorado JC, Arias-Nuñez MC, Miranda-Filloy JA, Gonzalez-Juanatey C, Llorca J, and Gonzalez-Gay MA

Subjects
CREST Syndrome complications, CREST Syndrome diagnosis, Female, Hearing Loss, Sensorineural diagnosis, Humans, Male, Middle Aged, Nystagmus, Pathologic complications, Nystagmus, Pathologic diagnosis, Scleroderma, Systemic immunology, Vestibular Diseases diagnosis, Autoantibodies blood, Centromere Protein B immunology, Hearing Loss, Sensorineural complications, Scleroderma, Systemic complications, Vestibular Diseases complications
Abstract

Audiovestibular dysfunction has been reported in patients with connective tissue disease. Systemic sclerosis (SSc; scleroderma) is a rare connective tissue disease of unknown etiology. In the current study we assess whether audiovestibular involvement is present in patients with limited scleroderma (lSSc). To answer this question we studied a series of 35 consecutive patients who fulfilled well-established classification criteria for lSSc and had antibodies against the major centromere protein-B (CENP-B), and 59 matched controls. Individuals with a history of cerebrovascular complications, syphilis, Ménière and other vestibular syndromes, infections involving the inner ear, barotrauma, or in treatment with ototoxic drugs were excluded. The majority of patients with lSSc were women (94%). The mean age at time of study was 64.5 years, and the mean age at time of disease diagnosis was 56.9 years. Besides Raynaud phenomenon, most patients with lSSc had other typical features of CREST (calcinosis, Raynaud phenomenon, esophageal hypomotility, sclerodactyly, and telangiectasia) syndrome. Twenty-seven (77%) patients showed abnormal hearing loss in the audiogram compared with only 15 (26%) of the controls (p < 0.001). Values of audiometric tests (pure-tone average and speech reception threshold) yielded significant differences between patients and controls (p < 0.001). The typical pattern of hearing impairment in our series of lSSc patients was a bilateral and symmetrical sensorineural hearing loss with a flat pattern in the audiogram. Abnormal tympanogram and abnormal stapedial reflex were more commonly observed in patients than controls (p < or = 0.001). Similarly, a significantly increased frequency of abnormal oculocephalic response (10 patients, 29%) and head-shaking nystagmus (9 patients, 26%) was observed in patients compared with controls (p < 0.001 for both comparisons). Finally, a significantly increased frequency of abnormal caloric test and clinical test of sensory integration and balance was observed in lSSc patients (31% and 46% of patients, respectively) compared with controls (0% and 12%, respectively) (p < 0.001 for both comparisons). The current study demonstrates strong evidence for inner ear compromise in patients with lSSc.

Published
2008
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