1. Analyses and treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms.
- Author
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Cheng Y, Xue F, Wang TY, Ji JF, Chen W, Wang ZY, Xu L, Hang CH, and Liu XF
- Subjects
- Adolescent, Adult, Aftercare methods, Aged, Cerebrospinal Fluid Rhinorrhea etiology, Cerebrospinal Fluid Rhinorrhea therapy, Child, Epistaxis etiology, Epistaxis therapy, Female, Humans, Male, Middle Aged, Nasal Mucosa pathology, Nasal Septal Perforation etiology, Nasal Septal Perforation therapy, Nasal Surgical Procedures methods, Natural Orifice Endoscopic Surgery methods, Nose injuries, Nose surgery, Nose Diseases etiology, Olfactory Nerve Diseases etiology, Olfactory Nerve Diseases therapy, Paranasal Sinuses physiopathology, Postoperative Complications etiology, Recovery of Function, Retrospective Studies, Rhinitis, Atrophic etiology, Rhinitis, Atrophic therapy, Sphenoid Sinus surgery, Sphenoid Sinusitis etiology, Sphenoid Sinusitis therapy, Tissue Adhesions etiology, Tissue Adhesions therapy, Young Adult, Nasal Lavage methods, Natural Orifice Endoscopic Surgery adverse effects, Nose Diseases therapy, Pituitary Neoplasms surgery, Postoperative Complications therapy
- Abstract
In this study, we analyze and discuss the treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed and treated cases with nasal complications. After endonasal transsphenoidal resection of PNs, there were 26 cases of postoperative nasal complications (20.1%), including nasal hemorrhage (4.8%), cerebrospinal fluid rhinorrhea (6.9%), sphenoid sinusitis (2.3%), atrophic rhinitis (1.6%), olfactory disorder (1.6%), perforation of nasal septum (0.8%), and nasal adhesion (2.3%). All patients clinically recovered after therapy, which included treatment of the cavity through nasal endoscopy, intranasal corticosteroids, and nasal irrigation. We propose that regular nasal endoscopic review, specific nasal medications, and regular nasal irrigation can effectively clear nasal mucosal hyperemia-induced edema and nasal/nasoantral secretions, as well as promote regeneration of nasal mucosa, prevent nasal adhesion, maintain the sinus cavity drainage, and accelerate the recovery of the physiological function of the paranasal sinus. Timely treatment of patients with nasal complications after endonasal transsphenoidal resections of PNs could greatly relieve the clinical symptoms. Nasal cleaning is very beneficial to patients after surgery recovery.
- Published
- 2017
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