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Start Over Author "Bercik, Richard" Journal menopause
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2. Diminished vaginal HOXA13expression in women with pelvic organ prolapse

Author

Connell, Kathleen A., Guess, Marsha K., Tate, Alison, Andikyan, Vaagn, Bercik, Richard, and Taylor, Hugh S.

Abstract

Homeobox genes are transcriptional regulators that orchestrate embryonic development. The HOXA13gene is responsible for the development of the vagina and regulates extracellular matrix constituents. We hypothesized that vaginal expression of HOXA13may be decreased in women with pelvic organ prolapse (POP) and sought to determine if hypoestrogenism affects its expression.

Published
2009
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