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Your search keyword '"Liu, Junyan"' showing total 19 results
Start Over Author "Liu, Junyan" Journal microbial pathogenesis
19 results on '"Liu, Junyan"'

18. First report of novel genetic array aacA4 - bla IMP-25 - oxa30 - catB3 and identification of novel metallo-β-lactamase gene bla IMP25 : A Retrospective Study of antibiotic resistance surveillance on Psuedomonas aeruginosa in Guangzhou of South China, 2003–2007

Author

Yu, Guangchao, primary, Wen, Wangrong, additional, Peters, Brian M., additional, Liu, Junyan, additional, Ye, Congxiu, additional, Che, Yuchuan, additional, Liu, Juzhen, additional, Cao, Kaiyuan, additional, Xu, Zhenbo, additional, and Shirtliff, Mark E., additional

Published
2016
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19. Prevalence of GBS serotype III and identification of a ST 17-like genotype from neonates with invasive diseases in Guangzhou, China.

Author

Liu, Junyan, Xu, Ruirui, Zhong, Huamin, Zhong, Yukui, Xie, Yongqiang, Li, Lin, Li, Bing, Chen, Dingqiang, and Xu, Zhenbo

Subjects
*SEROTYPES, *GENOTYPES, *AGGLUTINATION, *POLYMERASE chain reaction, *CEREBROSPINAL meningitis, *SEPSIS, *POLYSACCHARIDES
Abstract

Abstract Objectives The aim of this study is to understand the surveillance of Streptococcus agalactiae (GBS) serotype and genotype which help developing specific vaccine for GBS infection. Methods The GBS serotype was determined by strep-B-Latex rapid agglutination method and multiplex PCR assay based on the differences among serotypes. Alleles and multilocus sequence types (MLST) were determined using the GBS MLST Website. Results Four GBS serotypes (Ia, Ib, III, and V) were identified, with serotype III which was intimately associated with purulent meningitis and sepsis, as the dominance. In EOD cases, sepsis and pneumonia showed dominance, but purulent meningitis was dominant in LOD cases. Also, a new ST-17 like type which might be a clone derive from ST-17 and emerge among neonatal disease cases was identified. Conclusions The prevalence of GBS serotype and genotype and their relation with GBS diseases guide the development of capsular polysaccharide vaccine. Highlights • Four GBS serotypes were identified, with type III intimately associated with purulent meningitis and sepsis, as dominance. • In EOD cases, sepsis and pneumonia showed dominance, but purulent meningitis was dominant in LOD cases. • A new ST-17 like type which might be a clone derive from ST-17 and emerge among neonatal disease cases was identified. [ABSTRACT FROM AUTHOR]

Published
2018
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