1. The thioredoxin reductase system of mycoplasmas
- Author
-
Ben-Menachem, G., Himmelreich, R., Herrmann, R., Aharonowitz, Y., and Rottem, S.
- Subjects
Mycoplasmatales -- Research ,Mycoplasma -- Research ,Biological sciences - Abstract
Mycoplasma capricolum and Mycoplasma pneumoniae were isolated and purified to understand the thioredoxin reductase system (NTS) in mycoplasmas. Results reveal that NTS activity on these mycoplasmas had an optimal ph of 6.5-7.5 and was dependent on NADPH as an electron donor. Furthermore, their cysteine dithiol active regions have isoleucine rather than threonine. Results also suggest that mycoplasmas may have evolved the NTS to protect themselves from the consequences of their self-generated oxidative challenge.
- Published
- 1997