1. The Effects of Carbonate on Candida albicans Filamentation, Biofilm Formation, and Antifungal Resistance.
- Author
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Miedema TP, Grooters KE, and Cleary IA
- Subjects
- Microbial Sensitivity Tests, Humans, Hyphae drug effects, Hyphae growth & development, Biofilms drug effects, Biofilms growth & development, Candida albicans drug effects, Candida albicans growth & development, Candida albicans physiology, Antifungal Agents pharmacology, Drug Resistance, Fungal, Carbonates pharmacology
- Abstract
Candida albicans, a member of the normal microbial population of healthy humans, is an opportunistic pathogen that can cause serious disease in immunocompromised patients. An important virulence factor of C. albicans is the formation of biofilms. These organized communities of cells are efficient at attaching to host cells and implanted medical devices. Carbonate has been studied as an agricultural antifungal agent, and here we demonstrate that carbonate can affect filamentation, biofilm formation, and antifungal drug resistance in C. albicans., (© 2024 The Author(s). MicrobiologyOpen published by John Wiley & Sons Ltd.)
- Published
- 2024
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