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Your search keyword '"Eriksson, Olof"' showing total 6 results
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6 results on '"Eriksson, Olof"'

1. Contributors

Author

Aarntzen, Erik, primary, Achilefu, Samuel, additional, Akam, Eman A., additional, Albaghdadi, Mazen, additional, Beer, Ambros J., additional, Bharti, Santosh, additional, Bhujwalla, Zaver M., additional, Bischof, Gérard N., additional, Biswal, Sandip, additional, Boss, Marti, additional, Botnar, René M., additional, Brinson, Zabecca, additional, Brom, Maarten, additional, Buitinga, Mijke, additional, Bulte, Jeff W.M., additional, Caravan, Peter, additional, Chan, Heang-Ping, additional, Chandy, Mark, additional, Chaney, Aisling M., additional, Chen, Delphine L., additional, Chen, Xiaoyuan (Shawn), additional, Chenevert, Thomas L., additional, Coughlin, Jennifer M., additional, Covington, Matthew F., additional, Cumming, Paul, additional, Daldrup-Link, Heike E., additional, Deal, Emily M., additional, de Galan, Bastiaan, additional, Derlin, Thorsten, additional, Dewhirst, Mark W., additional, Di Paolo, Arianna, additional, Drzezga, Alexander, additional, Du, Yong, additional, Thi-Quynh Duong, Mai, additional, Ehman, Richard L., additional, Eriksson, Olof, additional, Galli, Filippo, additional, Gatenby, Robert A., additional, Gelovani, Juri, additional, Giehl, Kathrin, additional, Giger, Maryellen L., additional, Goel, Reema, additional, Gold, Garry, additional, Gotthardt, Martin, additional, Graham, Michael M., additional, Gropler, Robert J., additional, Gründer, Gerhard, additional, Gulhane, Avanti, additional, Hadjiiski, Lubomir, additional, Hajhosseiny, Reza, additional, Hammoud, Dima A., additional, Helfer, Brooke M., additional, Hicks, Rodney J., additional, Higuchi, Takahiro, additional, Hoffman, John M., additional, Honer, Michael, additional, Huang, Sung-Cheng (Henry), additional, Hung, Jessica, additional, Hwang, Do Won, additional, Jackson, Isaac M., additional, Jacobs, Andreas H., additional, Jaffer, Farouc A., additional, Jain, Sanjay K., additional, James, Michelle L., additional, Jansen, Tom, additional, Johansson, Lars, additional, Joosten, Lieke, additional, Kakkad, Samata, additional, Kamson, David, additional, Kang, Sae-Ryung, additional, Kelly, Kimberly A., additional, Knopp, Michelle I., additional, Knopp, Michael V., additional, Kogan, Feliks, additional, Krishnamachary, Balaji, additional, Künnecke, Basil, additional, Lee, Dong Soo, additional, Libby, Peter, additional, Luker, Gary D., additional, Luker, Kathryn E., additional, Makowski, Marcus R., additional, Mankoff, David A., additional, Massoud, Tarik F., additional, Meyer, Charles R., additional, Miller, Zach, additional, Min, Jung-Joon, additional, Mondal, Suman B., additional, Montesi, Sydney B., additional, Navin, Patrick J., additional, Nekolla, Stephan G., additional, Niu, Gang, additional, Notohamiprodjo, Susan, additional, Ordoñez, Alvaro A., additional, Osborn, Eric A., additional, Pacheco-Torres, Jesus, additional, Pagano, Gennaro, additional, Palmer, Gregory M., additional, Paulmurugan, Ramasamy, additional, Penet, Marie-France, additional, Phinikaridou, Alkystis, additional, Pomper, Martin G., additional, Prieto, Claudia, additional, Qi, Haikun, additional, Raghunand, Natarajan, additional, Ramar, Thangam, additional, Reynolds, Fred, additional, Ropella-Panagis, Kathleen, additional, Ross, Brian D., additional, Rowe, Steven P., additional, Rudin, Markus, additional, Sadaghiani, Mohammad S., additional, Sager, Hendrik, additional, Samala, Ravi, additional, Saraste, Antti, additional, Schelhaas, Sonja, additional, Schwaiger, Markus, additional, Schwarz, Sally W., additional, Seiberlich, Nicole, additional, Shapiro, Mikhail G., additional, Shim, Hyunsuk, additional, Signore, Alberto, additional, Solnes, Lilja B., additional, Suh, Minseok, additional, Tsien, Christina, additional, van Eimeren, Thilo, additional, Varasteh, Zohreh, additional, Venkatesh, Sudhakar Kundapur, additional, Viel, Thomas, additional, Waerzeggers, Yannic, additional, Wahl, Richard L., additional, Weber, Wolfgang, additional, Werner, Rudolf A., additional, Winkeler, Alexandra, additional, Wong, Dean F., additional, Wright, Chadwick L., additional, Wu, Anna M., additional, Wu, Joseph C., additional, Yoon, Daehyun, additional, You, Sung-Hwan, additional, Yuan, Chun, additional, Yuan, Hong, additional, Zanzonico, Pat, additional, Zhao, Xue-Qiao, additional, Zhou, Iris Y., additional, and Zinnhardt, Bastian, additional

Published
2021
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2. Molecular Imaging of Diabetes

Author

Joosten, Lieke, primary, Boss, Marti, additional, Jansen, Tom, additional, Brom, Maarten, additional, Buitinga, Mijke, additional, Aarntzen, Erik, additional, Eriksson, Olof, additional, Johansson, Lars, additional, de Galan, Bastiaan, additional, and Gotthardt, Martin, additional

Published
2021
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5. [11C]Carfentanil Binds Preferentially to µ-Opioid Receptor Subtype 1 Compared to Subtype 2.

Author

Eriksson, Olof and Antoni, Gunnar

Subjects
*OPIOID receptors, *POSITRON emission tomography, *LABORATORY rats, *FENTANYL, *MEDICAL sciences
Abstract

The positron emission tomography (PET) ligand [11C]carfentanil is a selective agonist for μ-opioid receptors and has been used for studying μ-opioid receptors in the human brain. However, it is unknown if [11C]carfentanil binding differentiates between subtype receptors μ1 and μ2. In this study, we investigated whether μ1 and μ2 can be studied separately through receptor subtype–selective inhibition of [11C]carfentanil by pharmacologic intervention. [11C]Carfentanil binding characteristics on rat brain sections were assessed either alone or in the presence of the μ-receptor inhibitor cyprodime or the μ1-specific inhibitor naloxonazine. [11C]Carfentanil binding in the living rat brain was similarly studied by small animal PET/computed tomography during baseline conditions or following displacement by cyprodime or naloxonazine. Autoradiography binding studies on rat brain sections demonstrated that [11C]carfentanil has higher affinity and binding potential for μ1 than for μ2. [11C]Carfentanil binding to μ2 in vivo could not be detected following specific blocking of μ1, as predicted from the low binding potential for μ2 as measured in vitro. [11C]Carfentanil binding is preferential for μ1 compared to μ2 in vitro and in vivo. Clinical studies employing [11C]carfentanil are therefore likely biased to measure μ1 rather than μ2. [ABSTRACT FROM AUTHOR]

Published
2015
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6. [11C]Carfentanil Binds Preferentially to μ-Opioid Receptor Subtype 1 Compared to Subtype 2.

Author

Eriksson O and Antoni G

Subjects
Animals, Autoradiography, Carbon Radioisotopes, Fentanyl metabolism, Frozen Sections, Kinetics, Male, Positron-Emission Tomography, Protein Binding, Rats, Sprague-Dawley, Fentanyl analogs & derivatives, Receptors, Opioid, mu metabolism
Abstract

The positron emission tomography (PET) ligand [(11)C]carfentanil is a selective agonist for μ-opioid receptors and has been used for studying μ-opioid receptors in the human brain. However, it is unknown if [(11)C]carfentanil binding differentiates between subtype receptors μ1 and μ2. In this study, we investigated whether μ1 and μ2 can be studied separately through receptor subtype-selective inhibition of [(11)C]carfentanil by pharmacologic intervention. [(11)C]Carfentanil binding characteristics on rat brain sections were assessed either alone or in the presence of the μ-receptor inhibitor cyprodime or the μ1-specific inhibitor naloxonazine. [(11)C]Carfentanil binding in the living rat brain was similarly studied by small animal PET/computed tomography during baseline conditions or following displacement by cyprodime or naloxonazine. Autoradiography binding studies on rat brain sections demonstrated that [(11)C]carfentanil has higher affinity and binding potential for μ1 than for μ2. [(11)C]Carfentanil binding to μ2 in vivo could not be detected following specific blocking of μ1, as predicted from the low binding potential for μ2 as measured in vitro. [(11)C]Carfentanil binding is preferential for μ1 compared to μ2 in vitro and in vivo. Clinical studies employing [(11)C]carfentanil are therefore likely biased to measure μ1 rather than μ2.

Published
2015

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