1. Promoting Artemisinin Biosynthesis in Artemisia annua Plants by Substrate Channeling
- Author
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Hongzhen Wang, Mengshu Hao, Anneli Lundgren, Peter E. Brodelius, Junli Han, and Selvaraju Kanagarajan
- Subjects
0106 biological sciences ,0301 basic medicine ,Traditional medicine ,Substrate channeling ,Artemisia annua ,Plant Science ,Biology ,medicine.disease ,biology.organism_classification ,Plants, Genetically Modified ,01 natural sciences ,humanities ,Artemisinins ,03 medical and health sciences ,030104 developmental biology ,Gene Expression Regulation, Plant ,parasitic diseases ,medicine ,Artemisinin ,Molecular Biology ,Malaria ,010606 plant biology & botany ,medicine.drug - Abstract
Professor Youyou Tu, China Academy of Chinese Medical Sciences, Beijing, was awarded the 2015 Nobel Prize in Physiology or Medicine for “her discoveries concerning a novel therapy against malaria” (https://www.nobelprize.org/nobel_prizes/medicine/laureates/2015/press.html). This therapy is based on the sesquiterpenoid artemisinin, isolated from Artemisia annua. Artemisinin and its derivatives, administered in the form of artemisinin-based combination therapies (ACTs), are currently the best treatment for malaria.
- Published
- 2015