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Start Over Author "Hao Tong" Journal molecular systems biology
7 results on '"Hao Tong"'

1. AI-guided pipeline for protein–protein interaction drug discovery identifies a SARS-CoV-2 inhibitor

Author

Trepte, Philipp, Secker, Christopher, Olivet, Julien, Blavier, Jeremy, Kostova, Simona, Maseko, Sibusiso B, Minia, Igor, Silva Ramos, Eduardo, Cassonnet, Patricia, Golusik, Sabrina, Zenkner, Martina, Beetz, Stephanie, Liebich, Mara J, Scharek, Nadine, Schütz, Anja, Sperling, Marcel, Lisurek, Michael, Wang, Yang, Spirohn, Kerstin, Hao, Tong, Calderwood, Michael A, Hill, David E, Landthaler, Markus, Choi, Soon Gang, Twizere, Jean-Claude, Vidal, Marc, and Wanker, Erich E

Published
2024
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2. Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Author

Yachie, Nozomu, primary, Petsalaki, Evangelia, additional, Mellor, Joseph C, additional, Weile, Jochen, additional, Jacob, Yves, additional, Verby, Marta, additional, Ozturk, Sedide B, additional, Li, Siyang, additional, Cote, Atina G, additional, Mosca, Roberto, additional, Knapp, Jennifer J, additional, Ko, Minjeong, additional, Yu, Analyn, additional, Gebbia, Marinella, additional, Sahni, Nidhi, additional, Yi, Song, additional, Tyagi, Tanya, additional, Sheykhkarimli, Dayag, additional, Roth, Jonathan F, additional, Wong, Cassandra, additional, Musa, Louai, additional, Snider, Jamie, additional, Liu, Yi‐Chun, additional, Yu, Haiyuan, additional, Braun, Pascal, additional, Stagljar, Igor, additional, Hao, Tong, additional, Calderwood, Michael A, additional, Pelletier, Laurence, additional, Aloy, Patrick, additional, Hill, David E, additional, Vidal, Marc, additional, and Roth, Frederick P, additional

Published
2016
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3. An inter‐species protein–protein interaction network across vast evolutionary distance

Author

Zhong, Quan, primary, Pevzner, Samuel J, additional, Hao, Tong, additional, Wang, Yang, additional, Mosca, Roberto, additional, Menche, Jörg, additional, Taipale, Mikko, additional, Taşan, Murat, additional, Fan, Changyu, additional, Yang, Xinping, additional, Haley, Patrick, additional, Murray, Ryan R, additional, Mer, Flora, additional, Gebreab, Fana, additional, Tam, Stanley, additional, MacWilliams, Andrew, additional, Dricot, Amélie, additional, Reichert, Patrick, additional, Santhanam, Balaji, additional, Ghamsari, Lila, additional, Calderwood, Michael A, additional, Rolland, Thomas, additional, Charloteaux, Benoit, additional, Lindquist, Susan, additional, Barabási, Albert‐László, additional, Hill, David E, additional, Aloy, Patrick, additional, Cusick, Michael E, additional, Xia, Yu, additional, Roth, Frederick P, additional, and Vidal, Marc, additional

Published
2016
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4. SH3 interactome conserves general function over specific form

Author

Xin, Xiaofeng, primary, Gfeller, David, additional, Cheng, Jackie, additional, Tonikian, Raffi, additional, Sun, Lin, additional, Guo, Ailan, additional, Lopez, Lianet, additional, Pavlenco, Alevtina, additional, Akintobi, Adenrele, additional, Zhang, Yingnan, additional, Rual, Jean‐François, additional, Currell, Bridget, additional, Seshagiri, Somasekar, additional, Hao, Tong, additional, Yang, Xinping, additional, Shen, Yun A, additional, Salehi‐Ashtiani, Kourosh, additional, Li, Jingjing, additional, Cheng, Aaron T, additional, Bouamalay, Dryden, additional, Lugari, Adrien, additional, Hill, David E, additional, Grimes, Mark L, additional, Drubin, David G, additional, Grant, Barth D, additional, Vidal, Marc, additional, Boone, Charles, additional, Sidhu, Sachdev S, additional, and Bader, Gary D, additional

Published
2013
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6. Edgetic perturbation models of human inherited disorders

Author

Zhong, Quan, primary, Simonis, Nicolas, additional, Li, Qian‐Ru, additional, Charloteaux, Benoit, additional, Heuze, Fabien, additional, Klitgord, Niels, additional, Tam, Stanley, additional, Yu, Haiyuan, additional, Venkatesan, Kavitha, additional, Mou, Danny, additional, Swearingen, Venus, additional, Yildirim, Muhammed A, additional, Yan, Han, additional, Dricot, Amélie, additional, Szeto, David, additional, Lin, Chenwei, additional, Hao, Tong, additional, Fan, Changyu, additional, Milstein, Stuart, additional, Dupuy, Denis, additional, Brasseur, Robert, additional, Hill, David E, additional, Cusick, Michael E, additional, and Vidal, Marc, additional

Published
2009
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7. Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism.

Author

Chang, Roger L, Ghamsari, Lila, Manichaikul, Ani, Hom, Erik F Y, Balaji, Santhanam, Fu, Weiqi, Shen, Yun, Hao, Tong, Palsson, Bernhard Ø, Salehi‐Ashtiani, Kourosh, and Papin, Jason A

Abstract

Metabolic network reconstruction encompasses existing knowledge about an organism’s metabolism and genome annotation, providing a platform for omics data analysis and phenotype prediction. The model alga Chlamydomonas reinhardtii is employed to study diverse biological processes from photosynthesis to phototaxis. Recent heightened interest in this species results from an international movement to develop algal biofuels. Integrating biological and optical data, we reconstructed a genome-scale metabolic network for this alga and devised a novel light-modeling approach that enables quantitative growth prediction for a given light source, resolving wavelength and photon flux. We experimentally verified transcripts accounted for in the network and physiologically validated model function through simulation and generation of new experimental growth data, providing high confidence in network contents and predictive applications. The network offers insight into algal metabolism and potential for genetic engineering and efficient light source design, a pioneering resource for studying light-driven metabolism and quantitative systems biology. [ABSTRACT FROM AUTHOR]

Published
2011
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