1. SERS-Based Aptasensor for Rapid Quantitative Detection of SARS-CoV-2.
- Author
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Zavyalova, Elena, Ambartsumyan, Oganes, Zhdanov, Gleb, Gribanyov, Dmitry, Gushchin, Vladimir, Tkachuk, Artem, Rudakova, Elena, Nikiforova, Maria, Kuznetsova, Nadezhda, Popova, Liubov, Verdiev, Bakhtiyar, Alatyrev, Artem, Burtseva, Elena, Ignatieva, Anna, Iliukhina, Anna, Dolzhikova, Inna, Arutyunyan, Alexander, Gambaryan, Alexandra, and Kukushkin, Vladimir
- Subjects
SARS-CoV-2 ,SERS spectroscopy ,COVID-19 pandemic ,OLIGONUCLEOTIDES ,APTAMERS ,VIRUS diseases - Abstract
During the COVID-19 pandemic, the development of sensitive and rapid techniques for detection of viruses have become vital. Surface-enhanced Raman scattering (SERS) is an appropriate tool for new techniques due to its high sensitivity. SERS materials modified with short-structured oligonucleotides (DNA aptamers) provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection are either inapplicable for quantitative determination or have sophisticated and expensive construction and implementation. In this paper, we provide a SERS-aptasensor based on colloidal solutions which combines rapidity and specificity in quantitative determination of SARS-CoV-2 virus, discriminating it from the other respiratory viruses. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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