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James P. Allison from the MD Anderson Cancer Center, University of Texas, and Tasuku Honjo from Kyoto university were jointly awarded the prestigious Nobel Prize in Physiology/Medicine 2018. Their therapeutic research is on the inhibition of CTLA-4 and PD-1, two proteins which act as a blockade and prevent the immune system from attacking tumor cells.

The Nobel Prize in Physics 2018 was awarded jointly to Arthur Ashkin, Gerard Mourou and Donna Strickland for giving new beam of light in the field of laser physics. Unravelling new mechanical properties of biological molecule has made an interdisciplinary approach with physics creating significant insight into solving devil diseases.

Nobel committee has awarded William G. Kaelin, Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza Nobel Prize in Medicine this year for their remarkable discoveries in how cell sense low level of oxygen and rapidly adapts to the changing environment. Hypoxia is often considered to be the main regulator of cancer, since it promotes metabolic changes of the cell. Inhibition of signal transduction pathway and transcriptional regulators can be used as a therapeutic approach to control cancer progression.

Nobel Prize in Physiology or Medicine 2017 is awarded jointly to Hall, Rosbash and Young for their phenomenal discovery of tiny biological clock working in every living being helping the anticipation and adaptation of biological rhythms to get synchronized with Earth’s evolution.

Yoshinori Ohsumi from Tokyo Institute of Technology of Japan had received the prestigious Nobel Prize in Physiology or Medicine 2016 for discovering the mechanism of cell’s self-eating autophagy, which is remarkable research in itself for cellular suicidal mediated cell recycling.

Baratang mud volcano of Andaman and Nicobar Islands is a noteworthy earthquake-triggered mud volcanic signature of India where only a few detailed works are done on microfossils and gas composition. This updated compilation and present-day detailing on Baratang may draw more attention of researchers to it resulting in important findings.