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1. An Unprecedented High Content of the Bioactive Flavone Tricin in Huperzia Medicinal Species Used by the Saraguro in Ecuador.

Author

Armijos C, Ponce J, Ramírez J, Gozzini D, Finzi PV, and Vidari G

Subjects
Chromatography, High Pressure Liquid methods, Ecuador, Humans, Mass Spectrometry methods, Medicine, Traditional, Flavonoids chemistry, Flavonoids pharmacology, Huperzia chemistry, Plants, Medicinal chemistry, Population Groups
Abstract

The flavone tricin (5,7,4'-trihydroxy-3',5'-dimethoxyflavone) is considered to be a selective potent inhibitor of different cancer cell lines and a potential colorectal cancer chemopreventive agent. In this paper we describe a reliable UHPLC-UV-ESIMS method for the determination of tricin in Huperzia plants used in the traditional medicine of the Saraguro community living in Southern Ecuador. An unusually high amount of tricin was found in H. brevifolia and H. compacta, which exceeded the content of this flavone determined so far in other plants.

Published
2016

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