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Your search keyword '"Eman Maher Zahran"' showing total 6 results
Start Over Author "Eman Maher Zahran" Journal natural product research
6 results on '"Eman Maher Zahran"'

1. Cytotoxic and anti-diabetic potential, metabolic profiling and insilico studies of Syzygium cumini (L.) Skeels belonging to family Myrtaceae

Author

Merivat Ahmed Fouad, Amany A. Sleem, Amira Kamal Eldin Elmotyam, Seham S. El-Hawary, Eman Maher Zahran, Anber F. Mohammed, Alaa M. Hayallah, Hanan Elimam, Usama Ramadan Abdelmohsen, Doaa Kamel Alsayed, and Mohamed H Rashed

Subjects
Traditional medicine, 010405 organic chemistry, Organic Chemistry, Plant Science, Biology, biology.organism_classification, 01 natural sciences, Biochemistry, 0104 chemical sciences, Analytical Chemistry, Family myrtaceae, 010404 medicinal & biomolecular chemistry, DNA profiling, Syzygium, Cytotoxic T cell
Abstract

LC-HR-MS-coupled metabolic profiling of the methanol extracts from different parts of Syzygium cumini (L.), which was extensively identified via DNA fingerprinting, led to dereplication of 24 compo...

Published
2020

2. Anti-epileptic potential, metabolic profiling and in silico studies of the aqueous fraction from Ocimum menthiifolium benth, family Lamiaceae

Author

Samar Yehia Desoukey, M. Alaraby Salem, Usama Ramadan Abdelmohsen, Mohamed Kamel, Ahmed Kolkeila, Hany Ezzat Khalil, Mostafa A. Fouad, and Eman Maher Zahran

Subjects
Family Lamiaceae, Aqueous solution, Biochemistry, biology, Chemistry, In silico, Organic Chemistry, Plant Science, Ocimum, biology.organism_classification, Analytical Chemistry
Abstract

The current study aimed to investigate the anti-epileptic potential of the ethanol extract and its different fractions from the Lamiaceous plant, Ocimum menthiifolium. The results revealed that the aqueous fraction with the latest onset of myoclonic convulsions (1095 ± 45**** s) was the most biologically active one. This was followed by LC-HR-MS-coupled metabolic profiling which led to dereplication of 8 compounds from that fraction. A molecular docking study was performed on the dereplicated compounds to discover the main responsible ones for the activity. The results highlighted Apigenin-7,4'-di-O-glucoside as the top scoring ligand with a possible mechanism of action involving the modulation of the voltage-gated sodium channel.

Published
2020

3. Cytotoxic and anti-diabetic potential, metabolic profiling and

Author

Seham Salah, Eldin Elhawary, Amira Kamal Eldin, Elmotyam, Doaa Kamel, Alsayed, Eman Maher, Zahran, Merivat Ahmed, Fouad, Amany Ameen, Sleem, Hanan, Elimam, Mohamed H, Rashed, Alaa M, Hayallah, Anber F, Mohammed, and Usama Ramadan, Abdelmohsen

Subjects
Molecular Docking Simulation, Plant Leaves, Plant Extracts, Myrtaceae, Syzygium
Abstract

LC-HR-MS-coupled metabolic profiling of the methanol extracts from different parts of

Published
2020

4. Anti-epileptic potential, metabolic profiling and in silico studies of the aqueous fraction from

Author

Eman Maher, Zahran, Usama Ramadan, Abdelmohsen, Ahmed, Kolkeila, M Alaraby, Salem, Hany Ezzat, Khalil, Samar Yehia, Desoukey, Mostafa Ahmed, Fouad, and Mohamed Salah, Kamel

Subjects
Molecular Docking Simulation, Lamiaceae, Ocimum, Plant Extracts, Ocimum basilicum
Abstract

The current study aimed to investigate the anti-epileptic potential of the ethanol extract and its different fractions from the

Published
2020

5. Local anaesthetic potential, metabolic profiling, molecular docking and in silico ADME studies of

Author

Eman Maher, Zahran, Usama Ramadan, Abdelmohsen, Mahmoud M, Shalash, M Alaraby, Salem, Hany Ezzat, Khalil, Samar Yehia, Desoukey, Mostafa Ahmed, Fouad, Markus, Krischke, Martin, Mueller, and Mohamed Salah, Kamel

Subjects
Molecular Docking Simulation, Ocimum, Ocimum basilicum, Anesthetics, Local, Anesthesia, Local
Abstract

The present study aimed to detect the bioactive metabolites from

Published
2020

6. Antiulcer potential and molecular docking of flavonoids from

Author

Eman Maher, Zahran, Usama Ramadan, Abdelmohsen, A Samir, Hussein, M Alaraby, Salem, Hany Ezzat, Khalil, Samar, Yehia Desoukey, Mostafa Ahmed, Fouad, and Mohamed Salah, Kamel

Subjects
Flavonoids, Molecular Docking Simulation, Ethanol, Ocimum, Plant Extracts, Catalytic Domain, Phytochemicals, Solvents, Toxicity Tests, Acute, Acetates, Molecular Dynamics Simulation, Anti-Ulcer Agents, Ulcer
Abstract

The present study aimed to detect the bioactive metabolites from

Published
2019

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