1. Thujasutchins N and O, two new compounds from the stems and roots of Thuja sutchuenensis.
- Author
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Wang, Miaomiao, Huo, Luqiong, Liu, Hongxin, Zhao, Liyun, Xu, Zhifang, Tan, Haibo, and Qiu, Sheng-Xiang
- Subjects
METABOLITES ,SINGLE crystals ,X-ray diffraction ,ANTIBACTERIAL agents ,SKELETON - Abstract
Two novel secondary metabolites, including one thujopsene-type sesquiterpene designated thujasutchin N (1) and one norlignan named thujasutchin O (2) were obtained from the ethanolic extract of the stems and roots of Thuja sutchuenensis. Among them, thujasutchin O (2) represents the first example of lignan sharing a unique carbon-reduced skeleton with novel acetal functionality. Their structures were unambiguously determined by means of extensively spectroscopic analysis including UV, IR, HRESIMS, NMR, and single crystal X-ray diffraction. Both of the isolates were evaluated for their in vitro cytotoxic and antibacterial activities. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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