1. The mutational landscape of lethal castration-resistant prostate cancer
- Author
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Grasso, Catherine S., Wu, Yi-Mi, Robinson, Dan R., Cao, Xuhong, Dhanasekaran, Saravana M., Khan, Amjad P., Quist, Michael J., Jing, Xiaojun, Lonigro, Robert J., Brenner, J. Chad, Asangani, Irfan A., Ateeq, Bushra, Chun, Sang Y., Siddiqui, Javed, Sam, Lee, Anstett, Matt, Mehra, Rohit, Prensner, John R., Palanisamy, Nallasivam, Ryslik, Gregory A., Vandin, Fabio, Raphael, Benjamin J., Kunju, Lakshmi P., Rhodes, Daniel R., Pienta, Kenneth J., Chinnaiyan, Arul M., and Tomlins, Scott A.
- Subjects
Development and progression ,Genetic aspects ,Research ,Health aspects ,Gene mutation -- Health aspects -- Research ,Prostate cancer -- Development and progression -- Genetic aspects -- Research ,Gene mutations -- Health aspects -- Research - Abstract
Characterization of the prostate cancer transcriptome and genome has identified chromosomal rearrangements and copy number gains and losses, including ETS gene family fusions, PTEN loss and androgen receptor (AR) amplification, [...]
- Published
- 2012