Author: "Sullenger, Bruce A." / Journal: nature - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Sullenger, Bruce A." Journal nature

Author: Rusconi, Christopher P., Scardino, Elizabeth, Layzer, Juliana, Pitoc, George A., Ortel, Thomas L., Monroe, Dougald, and Sullenger, Bruce A.
Subjects: Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract: Author(s): Christopher P. Rusconi (corresponding author) [1]; Elizabeth Scardino [1]; Juliana Layzer [1]; George A. Pitoc [1]; Thomas L. Ortel [2]; Dougald Monroe [3]; Bruce A. Sullenger (corresponding author) [1] [...]
Published: 2002
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Author: Sullenger, Bruce A. and Gilboa, Eli
Subjects: Gene expression -- Health aspects -- Usage, RNA -- Health aspects -- Usage, Environmental issues, Science and technology, Zoology and wildlife conservation, Usage, Health aspects
Abstract: Author(s): Bruce A. Sullenger (corresponding author); Eli Gilboa The concept of using RNA molecules as therapeutic agents is relatively new, but has received increasing attention during the past decade. Much [...]
Published: 2002
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Author: Sullenger, Bruce A. and Cech, Thomas
Subjects: Catalytic RNA -- Observations, RNA splicing -- Analysis, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract: Targeted trans-splicing of ribozymes enables them to function as substitutes for defective RNA sections in a functional sequence, thus helping in the development of new treatments for genetic diseases. The self-splicing group I intron from Tetrahymena thermophila helps in the trans-splicing by reproducing the coding capacity of truncated lacZ transcripts. The in vitro trans-splicing yields translatable lacZ messages and constitutes a new method for the sequence modification of transcripts.
Published: 1994

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